Neuroleptic drugs in dementia: benefits and harm

C Ballard; R Howard

doi:10.1038/nrn1926

Neuroleptic drugs in dementia: benefits and harm

C Ballard, R Howard

Research output: Contribution to journal › Literature review › peer-review

236 Citations (Scopus)

Abstract

Neuroleptic (antipsychotic) drugs are often used to treat psychiatric symptoms frequently seen in dementia, but their use is controversial. We present a new meta-analysis to assess the efficacy of these drugs for the treatment of psychiatric symptoms in Alzheimer's disease, and discuss the more limited evidence for their potential benefits in other dementias. We recommend that these treatments be limited to the short-term treatment of psychiatric symptoms associated with serious distress or risk

Original language	English
Pages (from-to)	492 - 500
Number of pages	9
Journal	NATURE REVIEWS NEUROSCIENCE
Volume	7
Issue number	6
DOIs	https://doi.org/10.1038/nrn1926
Publication status	Published - Jun 2006

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10.1038/nrn1926

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title = "Neuroleptic drugs in dementia: benefits and harm",

abstract = "Neuroleptic (antipsychotic) drugs are often used to treat psychiatric symptoms frequently seen in dementia, but their use is controversial. We present a new meta-analysis to assess the efficacy of these drugs for the treatment of psychiatric symptoms in Alzheimer's disease, and discuss the more limited evidence for their potential benefits in other dementias. We recommend that these treatments be limited to the short-term treatment of psychiatric symptoms associated with serious distress or risk",

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AB - Neuroleptic (antipsychotic) drugs are often used to treat psychiatric symptoms frequently seen in dementia, but their use is controversial. We present a new meta-analysis to assess the efficacy of these drugs for the treatment of psychiatric symptoms in Alzheimer's disease, and discuss the more limited evidence for their potential benefits in other dementias. We recommend that these treatments be limited to the short-term treatment of psychiatric symptoms associated with serious distress or risk

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Neuroleptic drugs in dementia: benefits and harm

Abstract

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