New Insights into the Pathogenesis of Periodontal Diseases

Svetislav Zaric*, Mark Ide, Luigi Nibali

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review


Throughout our lives, we continuously encounter micro-organisms that range from those essential for health, to those causing diseases. The oral cavity is permanently colonized by micro-organisms and our immune system has a challenging role in maintaining oral homeostasis by balancing its responses to this unique microbiota, while preserving the structural integrity of oral tissues. This article discusses relationships between oral microbial community structure and activity, specifically addressing the role of low-abundance microbial species and their interplay with the host immune system, in view of the pathogenesis of dental plaque-induced periodontal conditions.
Original languageEnglish
Pages (from-to)314-317
Number of pages4
JournalDental Update
Issue number4
Publication statusPublished - 19 Apr 2022


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