New-Onset Diabetes in Covid-19

Francesco Rubino; Stephanie Amiel; Paul Z. Zimmet; Kurt George Alberti; Stefan Bornstein; Robert H. Eckel; Geltrude Mingrone; Bernhard Boehm; Mark Cooper; zhonglin chai; Stefano Del Prato; Linong Ji; David Hopkins; William Herman; Kamlesh Khunti; Jean Claude N. Mbanya; Eric Renard

doi:10.1056/NEJMc2018688

New-Onset Diabetes in Covid-19

Francesco Rubino, Stephanie Amiel, Paul Z. Zimmet, Kurt George Alberti, Stefan Bornstein, Robert H. Eckel, Geltrude Mingrone, Bernhard Boehm, Mark Cooper, zhonglin chai, Stefano Del Prato, Linong Ji, David Hopkins, William Herman, Kamlesh Khunti, Jean Claude N. Mbanya, Eric Renard

Diabetes

Research output: Contribution to journal › Letter › peer-review

583 Citations (Scopus)

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Abstract

There is a bidirectional relationship between Covid-19 and diabetes. On the one
hand, diabetes is associated with an increased risk of severe Covid-19. On the other hand, newonset diabetes and severe metabolic complications of preexisting diabetes, including diabetic ketoacidosis and hyperosmolarity for which exceptionally high doses of insulin are warranted, have been observed in patients with Covid-19.1-3
These manifestations of diabetes pose challenges in clinical management and suggest a complex pathophysiology of Covid-19–related diabetes.

Original language	English
Pages (from-to)	789-791
Number of pages	3
Journal	New England Journal of Medicine
Volume	383
Issue number	8
Early online date	12 Jun 2020
DOIs	https://doi.org/10.1056/NEJMc2018688
Publication status	Published - 20 Aug 2020

Keywords

diabetes, COVID-19, SARS-Cov-2, DKA

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1056/NEJMc2018688

New-Onset Diabetes_RUBINO_Accepted2020_GREEN VoRFinal published version, 311 KB

Cite this

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title = "New-Onset Diabetes in Covid-19",

abstract = "There is a bidirectional relationship between Covid-19 and diabetes. On the onehand, diabetes is associated with an increased risk of severe Covid-19. On the other hand, newonset diabetes and severe metabolic complications of preexisting diabetes, including diabetic ketoacidosis and hyperosmolarity for which exceptionally high doses of insulin are warranted, have been observed in patients with Covid-19.1-3These manifestations of diabetes pose challenges in clinical management and suggest a complex pathophysiology of Covid-19–related diabetes.",

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doi = "10.1056/NEJMc2018688",

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T1 - New-Onset Diabetes in Covid-19

AU - Rubino, Francesco

AU - Amiel, Stephanie

AU - Zimmet, Paul Z.

AU - Alberti, Kurt George

AU - Bornstein, Stefan

AU - Eckel, Robert H.

AU - Mingrone, Geltrude

AU - Boehm, Bernhard

AU - Cooper, Mark

AU - chai, zhonglin

AU - Del Prato, Stefano

AU - Ji, Linong

AU - Hopkins, David

AU - Herman, William

AU - Khunti, Kamlesh

AU - Mbanya, Jean Claude N.

AU - Renard, Eric

PY - 2020/8/20

Y1 - 2020/8/20

N2 - There is a bidirectional relationship between Covid-19 and diabetes. On the onehand, diabetes is associated with an increased risk of severe Covid-19. On the other hand, newonset diabetes and severe metabolic complications of preexisting diabetes, including diabetic ketoacidosis and hyperosmolarity for which exceptionally high doses of insulin are warranted, have been observed in patients with Covid-19.1-3These manifestations of diabetes pose challenges in clinical management and suggest a complex pathophysiology of Covid-19–related diabetes.

AB - There is a bidirectional relationship between Covid-19 and diabetes. On the onehand, diabetes is associated with an increased risk of severe Covid-19. On the other hand, newonset diabetes and severe metabolic complications of preexisting diabetes, including diabetic ketoacidosis and hyperosmolarity for which exceptionally high doses of insulin are warranted, have been observed in patients with Covid-19.1-3These manifestations of diabetes pose challenges in clinical management and suggest a complex pathophysiology of Covid-19–related diabetes.

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U2 - 10.1056/NEJMc2018688

DO - 10.1056/NEJMc2018688

M3 - Letter

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EP - 791

JO - New England Journal of Medicine

JF - New England Journal of Medicine

IS - 8

ER -

New-Onset Diabetes in Covid-19

Abstract

Keywords

UN SDGs

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