Abstract
The aim of this study is to investigate the clinical profile of patients who developed coronavirus disease 2019 (COVID-19) after full vaccination. Demographic, epidemiological and clinical data were collected through medical records and online patient-reported outcome questionnaire from patients who developed symptomatic SARS-CoV-2 infection, confirmed by nasopharyngeal swab, at least 2 weeks after completion of vaccination. A total of 153 subjects were included. The most frequent symptoms were: asthenia (82.4%), chemosensory dysfunction (63.4%), headache (59.5%), runny nose (58.2%), muscle pain (54.9%), loss of appetite (54.3%), and nasal obstruction (51.6%). Particularly, 62.3% and 53.6% of subjects reported olfactory and gustatory dysfunction, respectively. Symptom severity was mild or moderate in almost all cases. Chemosensory dysfunctions have been observed to be a frequent symptom even in subjects who contracted the infection after full vaccination. For this reason, the sudden loss of smell and taste could continue to represent a useful and specific diagnostic marker to raise the suspicion of COVID-19 even in vaccinated subjects. In the future, it will be necessary to establish what the recovery rate is in these patients. Level of Evidence: 4 Laryngoscope, 2021.
Original language | English |
---|---|
Pages (from-to) | 419-421 |
Number of pages | 3 |
Journal | Laryngoscope |
Volume | 132 |
Issue number | 2 |
Early online date | 26 Nov 2021 |
DOIs | |
Publication status | Published - Feb 2022 |
Keywords
- ageusia
- anosmia
- COVID-19
- gustatory dysfunction
- olfactory dysfunction
- vaccination