No effect of fish oil supplementation on serum inflammatory markers and their interrelationships: a randomized controlled trial in healthy, middle-aged individuals

G K Pot; I A Brouwer; A Enneman; G T Rijkers; E Kampman; A Geelen

doi:10.1038/ejcn.2009.63

No effect of fish oil supplementation on serum inflammatory markers and their interrelationships: a randomized controlled trial in healthy, middle-aged individuals

G K Pot, I A Brouwer, A Enneman, G T Rijkers, E Kampman, A Geelen

Nutritional Sciences

Research output: Contribution to journal › Article › peer-review

57 Citations (Scopus)

Abstract

A high intake of n-3 polyunsaturated fatty acids (PUFAs), mainly present in fish, may be associated with decreased inflammation. Previous intervention studies on fish PUFA and inflammatory markers in healthy individuals did not analyze a broad spectrum of inflammatory cytokines, chemokines and cell adhesion molecules, or their interrelationships. Therefore, we determined the effects of fish oil supplementation on 19 serum inflammatory markers and their interrelationships in healthy, middle-aged individuals.

Original language	English
Pages (from-to)	1353-9
Number of pages	7
Journal	European Journal of Clinical Nutrition
Volume	63
Issue number	11
DOIs	https://doi.org/10.1038/ejcn.2009.63
Publication status	Published - Nov 2009

Keywords

Chemokines
Double-Blind Method
Humans
Principal Component Analysis
Aged
Cell Adhesion Molecules
Inflammation
Dietary Fats, Unsaturated
Fatty Acids, Omega-3
Cytokines
Middle Aged
Dietary Supplements
Fish Oils
Male
Biological Markers
Female

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10.1038/ejcn.2009.63

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title = "No effect of fish oil supplementation on serum inflammatory markers and their interrelationships: a randomized controlled trial in healthy, middle-aged individuals",

abstract = "A high intake of n-3 polyunsaturated fatty acids (PUFAs), mainly present in fish, may be associated with decreased inflammation. Previous intervention studies on fish PUFA and inflammatory markers in healthy individuals did not analyze a broad spectrum of inflammatory cytokines, chemokines and cell adhesion molecules, or their interrelationships. Therefore, we determined the effects of fish oil supplementation on 19 serum inflammatory markers and their interrelationships in healthy, middle-aged individuals.",

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author = "Pot, {G K} and Brouwer, {I A} and A Enneman and Rijkers, {G T} and E Kampman and A Geelen",

year = "2009",

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doi = "10.1038/ejcn.2009.63",

language = "English",

volume = "63",

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T2 - a randomized controlled trial in healthy, middle-aged individuals

AU - Pot, G K

AU - Brouwer, I A

AU - Enneman, A

AU - Rijkers, G T

AU - Kampman, E

AU - Geelen, A

PY - 2009/11

Y1 - 2009/11

N2 - A high intake of n-3 polyunsaturated fatty acids (PUFAs), mainly present in fish, may be associated with decreased inflammation. Previous intervention studies on fish PUFA and inflammatory markers in healthy individuals did not analyze a broad spectrum of inflammatory cytokines, chemokines and cell adhesion molecules, or their interrelationships. Therefore, we determined the effects of fish oil supplementation on 19 serum inflammatory markers and their interrelationships in healthy, middle-aged individuals.

AB - A high intake of n-3 polyunsaturated fatty acids (PUFAs), mainly present in fish, may be associated with decreased inflammation. Previous intervention studies on fish PUFA and inflammatory markers in healthy individuals did not analyze a broad spectrum of inflammatory cytokines, chemokines and cell adhesion molecules, or their interrelationships. Therefore, we determined the effects of fish oil supplementation on 19 serum inflammatory markers and their interrelationships in healthy, middle-aged individuals.

KW - Chemokines

KW - Double-Blind Method

KW - Humans

KW - Principal Component Analysis

KW - Aged

KW - Cell Adhesion Molecules

KW - Inflammation

KW - Dietary Fats, Unsaturated

KW - Fatty Acids, Omega-3

KW - Cytokines

KW - Middle Aged

KW - Dietary Supplements

KW - Fish Oils

KW - Male

KW - Biological Markers

KW - Female

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DO - 10.1038/ejcn.2009.63

M3 - Article

C2 - 19623203

VL - 63

SP - 1353

EP - 1359

JO - European Journal of Clinical Nutrition

JF - European Journal of Clinical Nutrition

IS - 11

ER -

No effect of fish oil supplementation on serum inflammatory markers and their interrelationships: a randomized controlled trial in healthy, middle-aged individuals

Abstract

Keywords

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