Non-rigid image registration: theory and practice

W R Crum, T Hartkens, D L G Hill

Research output: Contribution to journalLiterature reviewpeer-review

547 Citations (Scopus)


Image registration is an important enabling technology in medical image analysis. The current emphasis is on development and validation of application-specific non-rigid techniques, but there is already a plethora of techniques and terminology in use. In this paper we discuss the current state of the art of non-rigid registration to put on-going research in context and to highlight current and future clinical applications that might benefit from this technology. The philosophy and motivation underlying non-rigid registration is discussed and a guide to common terminology is presented. The core components of registration systems are described and outstanding issues of validity and validation are confronted.
Original languageEnglish
Pages (from-to)S140 - S153
JournalBritish Journal of Radiology
Issue numberSPEC. ISS. 2
Publication statusPublished - 2004


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