Nonfatal congenital alveolar dysplasia due to abnormalities of NO synthase isoforms

S Hegde, S Pomplun, S Hannam, A Greenough

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    9 Citations (Scopus)

    Abstract

    Congenital alveolar dysplasia (CAD) is a rare disorder thought to represent alveolar growth arrest at the canalicular stage of development. An infant with CAD diagnosed on lung biopsy is reported, her respiratory problems resolved spontaneously and she was doing well at follow-up. The infant additionally suffered from systemic hypertension and hypertrophic pyloric stenosis. In conclusion, we speculate that the association of CAD with systemic hypertension and hypertrophic pyloric stenosis might be explained by abnormalities of isoforms of nitric oxide synthase (NOS) resulting in congenital deformities involving smooth muscles
    Original languageEnglish
    Pages (from-to)1248 - 1250
    Number of pages3
    JournalActa Paediatrica
    Volume96
    Issue number8
    DOIs
    Publication statusPublished - Aug 2007

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