Nonrigid Motion Modeling of the Liver From 3-D Undersampled Self-Gated Golden-Radial Phase Encoded MRI

Research output: Contribution to journalArticlepeer-review

55 Citations (Scopus)


Magnetic resonance imaging (MRI) has been commonly used for guiding and planning image guided interventions since it provides excellent soft tissue visualization of anatomy and allows motion modeling to predict the position of target tissues during the procedure. However, MRI-based motion modeling remains challenging due to the difficulty of acquiring multiple motion-free 3-D respiratory phases with adequate contrast and spatial resolution. Here, we propose a novel retrospective respiratory gating scheme from a 3-D undersampled high-resolution MRI acquisition combined with fast and robust image registrations to model the nonrigid deformation of the liver. The acquisition takes advantage of the recently introduced golden-radial phase encoding (G-RPE) trajectory. G-RPE is self-gated, i.e., the respiratory signal can be derived from the acquired data itself, and allows retrospective reconstructions of multiple respiratory phases at any arbitrary respiratory position. Nonrigid motion modeling is applied to predict the liver deformation of an average breathing cycle. The proposed approach was validated on 10 healthy volunteers. Motion model accuracy was assessed using similarity-, surface-, and landmark-based validation methods, demonstrating precise model predictions with an overall target registration error of TRE = 1.70 +/- 0.94 mm which is within the range of the acquired resolution.
Original languageEnglish
Article number6134675
Pages (from-to)805 - 815
Number of pages11
JournalIeee Transactions on Medical Imaging
Issue number3
Publication statusPublished - Mar 2012


Dive into the research topics of 'Nonrigid Motion Modeling of the Liver From 3-D Undersampled Self-Gated Golden-Radial Phase Encoded MRI'. Together they form a unique fingerprint.

Cite this