TY - JOUR
T1 - Nutrient, fibre and FODMAP intakes and food-related quality of life in patients with inflammatory bowel disease and their relationship with gastrointestinal symptoms of differing aetiologies
AU - Cox, Selina
AU - Clarke, Hazel
AU - O'Keeffe, Majella
AU - Dubois, Patrick C.
AU - Irving, Peter M.
AU - Lindsay, James O.
AU - Whelan, Kevin
PY - 2021/5/27
Y1 - 2021/5/27
N2 - Background and Aims: Certain foods are reported as gut symptom triggers in IBD, and fructans are shown to worsen non-inflammatory symptoms in inactive IBD, which may result in self-imposed dietary restrictions. The aim of this case-control study was therefore to investigate nutrient and FODMAP intakes, and the relationship between gut symptoms and dietary intake, in IBD.
Methods: Nutrient, fibre and FODMAP intakes were estimated using 7-day food records in patients with active IBD (Active IBD), inactive IBD with non-inflammatory gut symptoms (Inactive IBD-GI), inactive IBD without gut symptoms (Inactive IBD) and healthy controls. Nutrient, fibre and FODMAP intakes, numbers of participants achieving national nutrient recommendations, and food-related quality of life (FR-QoL) were compared across and between study groups, where appropriate.
Results: Food diaries were obtained from 232 patients with IBD (65 Active IBD, 86 Inactive IBD-GI, 81 Inactive IBD) and 84 healthy controls. Patients with Active IBD consumed significantly lower intakes of numerous micronutrients, including iron, folate, vitamin C, compared with healthy controls. All IBD groups consumed less total fibre (between 4.5 to 5.8 g/d) than healthy controls (P<0.001), while total FODMAP and fructan intakes were significantly lower in Active IBD compared with healthy controls. Strikingly, FR-QoL was significantly lower in all IBD groups compared with healthy controls (all P<0.001).
Conclusions: This study revealed significantly lower intakes of fibre, FODMAPs and micronutrients, in addition to poorer FR-QoL, in Active IBD and Inactive IBD-GI with gut symptoms compared with healthy controls. Future research should address dietary restrictions responsible for these differences.
AB - Background and Aims: Certain foods are reported as gut symptom triggers in IBD, and fructans are shown to worsen non-inflammatory symptoms in inactive IBD, which may result in self-imposed dietary restrictions. The aim of this case-control study was therefore to investigate nutrient and FODMAP intakes, and the relationship between gut symptoms and dietary intake, in IBD.
Methods: Nutrient, fibre and FODMAP intakes were estimated using 7-day food records in patients with active IBD (Active IBD), inactive IBD with non-inflammatory gut symptoms (Inactive IBD-GI), inactive IBD without gut symptoms (Inactive IBD) and healthy controls. Nutrient, fibre and FODMAP intakes, numbers of participants achieving national nutrient recommendations, and food-related quality of life (FR-QoL) were compared across and between study groups, where appropriate.
Results: Food diaries were obtained from 232 patients with IBD (65 Active IBD, 86 Inactive IBD-GI, 81 Inactive IBD) and 84 healthy controls. Patients with Active IBD consumed significantly lower intakes of numerous micronutrients, including iron, folate, vitamin C, compared with healthy controls. All IBD groups consumed less total fibre (between 4.5 to 5.8 g/d) than healthy controls (P<0.001), while total FODMAP and fructan intakes were significantly lower in Active IBD compared with healthy controls. Strikingly, FR-QoL was significantly lower in all IBD groups compared with healthy controls (all P<0.001).
Conclusions: This study revealed significantly lower intakes of fibre, FODMAPs and micronutrients, in addition to poorer FR-QoL, in Active IBD and Inactive IBD-GI with gut symptoms compared with healthy controls. Future research should address dietary restrictions responsible for these differences.
M3 - Article
SN - 1873-9946
JO - Journal of Crohn's & colitis
JF - Journal of Crohn's & colitis
ER -