Object priming and recognition memory: dissociable effects in left frontal cortex at encoding

TY - JOUR

T1 - Object priming and recognition memory

T2 - dissociable effects in left frontal cortex at encoding

AU - Spencer, Tom J

AU - Montaldi, Daniela

AU - Gong, Qi-Yong

AU - Roberts, Neil

AU - Mayes, Andrew R

PY - 2009/11

Y1 - 2009/11

N2 - Functional magnetic resonance imaging (fMRI) studies have implicated the left prefrontal cortex in priming. We tested the hypothesis that object encoding activity in different prefrontal cortex regions selectively predicts subsequent object priming and recognition respectively. Participants were scanned whilst making semantic category judgements about novel object pictures. One week later priming and recognition of these objects were tested. Encoding that produced long-lasting priming in the absence of recognition memory was associated with increased activity in left inferior prefrontal (BA 47) and superior frontal (BA 8) cortices. In contrast, encoding that produced object recognition one week later activated the left middle frontal cortex (BA 9). This is consistent with other evidence indicating that object priming and recognition are independent kind of memory. Problems of measuring item-by-item recognition and priming together are discussed.

AB - Functional magnetic resonance imaging (fMRI) studies have implicated the left prefrontal cortex in priming. We tested the hypothesis that object encoding activity in different prefrontal cortex regions selectively predicts subsequent object priming and recognition respectively. Participants were scanned whilst making semantic category judgements about novel object pictures. One week later priming and recognition of these objects were tested. Encoding that produced long-lasting priming in the absence of recognition memory was associated with increased activity in left inferior prefrontal (BA 47) and superior frontal (BA 8) cortices. In contrast, encoding that produced object recognition one week later activated the left middle frontal cortex (BA 9). This is consistent with other evidence indicating that object priming and recognition are independent kind of memory. Problems of measuring item-by-item recognition and priming together are discussed.

KW - Adult

KW - Female

KW - Frontal Lobe/physiology

KW - Functional Laterality/physiology

KW - Humans

KW - Magnetic Resonance Imaging

KW - Male

KW - Memory/physiology

KW - Pattern Recognition, Visual/physiology

KW - Prefrontal Cortex/physiology

KW - Psychomotor Performance/physiology

KW - Reaction Time/physiology

KW - Recognition, Psychology/physiology

U2 - 10.1016/j.neuropsychologia.2009.06.022

DO - 10.1016/j.neuropsychologia.2009.06.022

M3 - Article

C2 - 19563819

SN - 0028-3932

VL - 47

SP - 2942

EP - 2947

JO - Neuropsychologia

JF - Neuropsychologia

IS - 13

ER -