On-chip detection of radioactivity via silicon-based sensors for the quality control testing of radiopharmaceuticals

Matthew P. Taggart, Mark D. Tarn, Mohammad M.N. Esfahani, Stephen J. Archibald, Tom Deakin, Nicole Pamme*, Lee F. Thompson

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference paperpeer-review

2 Citations (Scopus)

Abstract

We present the use of highly sensitive, small footprint, low cost silicon photomultipliers (SiPM) for radioactivity detection in microfluidic channels, with a view to their integration into miniaturised quality control (QC) platforms for the testing of positron emission tomography (PET) radiopharmaceuticals. While SiPMs are light sensors, it was determined that they are also sensitive to other sources, e.g. direct interaction with positrons and gamma rays, making them suitable for radiation detection with standard chip materials, including those that are opaque, as well as for detection of gamma emitting radiotracers.

Original languageEnglish
Title of host publicationMicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences
PublisherChemical and Biological Microsystems Society
Pages1849-1851
Number of pages3
ISBN (Electronic)9780979806483
Publication statusPublished - 2015
Event19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2015 - Gyeongju, Korea, Republic of
Duration: 25 Oct 201529 Oct 2015

Publication series

NameMicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences

Conference

Conference19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2015
Country/TerritoryKorea, Republic of
CityGyeongju
Period25/10/201529/10/2015

Keywords

  • Positron emission tomography (PET)
  • Quality control (QC)
  • Radiation detection
  • Radiopharmaceuticals
  • Silicon photomultiplier (SiPM)

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