One brain, two selves

A A T S Reinders; E R S Nijenhuis; A M J Paans; J Korf; A T M Willemsen; J A den Boer

doi:10.1016/j.neuroimage.2003.08.021

One brain, two selves

A A T S Reinders, E R S Nijenhuis, A M J Paans, J Korf, A T M Willemsen, J A den Boer

Psychosis Studies

Research output: Contribution to journal › Article › peer-review

150 Citations (Scopus)

Abstract

Having a sense of self is an explicit and high-level functional specialization of the human brain. The anatomical localization of self-awareness and the brain mechanisms involved in consciousness were investigated by functional neuroimaging different emotional mental states of core consciousness in patients with Multiple Personality Disorder (i.e., Dissociative Identity Disorder (DID)). We demonstrate specific changes in localized brain activity consistent with their ability to generate at least two distinct mental states of self-awareness, each with its own access to autobiographical trauma-related memory. Our findings reveal the existence of different regional cerebral blood flow patterns for different senses of self. We present evidence for the medial prefrontal cortex (MPFC) and the posterior associative cortices to have an integral role in conscious experience.

Original language	English
Pages (from-to)	2119-2125
Number of pages	7
Journal	NeuroImage
Volume	20
Issue number	4
DOIs	https://doi.org/10.1016/j.neuroimage.2003.08.021
Publication status	Published - Dec 2003

Keywords

Adult
Brain
Cerebrovascular Circulation
Dissociative Disorders
Female
Humans
Image Processing, Computer-Assisted
Middle Aged
Multiple Personality Disorder
Wounds and Injuries

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10.1016/j.neuroimage.2003.08.021

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title = "One brain, two selves",

abstract = "Having a sense of self is an explicit and high-level functional specialization of the human brain. The anatomical localization of self-awareness and the brain mechanisms involved in consciousness were investigated by functional neuroimaging different emotional mental states of core consciousness in patients with Multiple Personality Disorder (i.e., Dissociative Identity Disorder (DID)). We demonstrate specific changes in localized brain activity consistent with their ability to generate at least two distinct mental states of self-awareness, each with its own access to autobiographical trauma-related memory. Our findings reveal the existence of different regional cerebral blood flow patterns for different senses of self. We present evidence for the medial prefrontal cortex (MPFC) and the posterior associative cortices to have an integral role in conscious experience.",

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doi = "10.1016/j.neuroimage.2003.08.021",

language = "English",

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T1 - One brain, two selves

AU - Reinders, A A T S

AU - Nijenhuis, E R S

AU - Paans, A M J

AU - Korf, J

AU - Willemsen, A T M

AU - den Boer, J A

PY - 2003/12

Y1 - 2003/12

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AB - Having a sense of self is an explicit and high-level functional specialization of the human brain. The anatomical localization of self-awareness and the brain mechanisms involved in consciousness were investigated by functional neuroimaging different emotional mental states of core consciousness in patients with Multiple Personality Disorder (i.e., Dissociative Identity Disorder (DID)). We demonstrate specific changes in localized brain activity consistent with their ability to generate at least two distinct mental states of self-awareness, each with its own access to autobiographical trauma-related memory. Our findings reveal the existence of different regional cerebral blood flow patterns for different senses of self. We present evidence for the medial prefrontal cortex (MPFC) and the posterior associative cortices to have an integral role in conscious experience.

KW - Adult

KW - Brain

KW - Cerebrovascular Circulation

KW - Dissociative Disorders

KW - Female

KW - Humans

KW - Image Processing, Computer-Assisted

KW - Middle Aged

KW - Multiple Personality Disorder

KW - Wounds and Injuries

U2 - 10.1016/j.neuroimage.2003.08.021

DO - 10.1016/j.neuroimage.2003.08.021

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SN - 1053-8119

VL - 20

SP - 2119

EP - 2125

JO - NeuroImage

JF - NeuroImage

IS - 4

ER -

One brain, two selves

Abstract

Keywords

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