Optobionic vision-a new genetically enhanced light on retinal prosthesis

TY - JOUR

T1 - Optobionic vision-a new genetically enhanced light on retinal prosthesis

AU - Degenaar, Patrick

AU - Grossman, Nir

AU - Memon, Muhammad Ali

AU - Burrone, Juan

AU - Dawson, Martin

AU - Drakakis, Emmanuel

AU - Neil, Mark

AU - Nikolic, Konstantin

PY - 2009

Y1 - 2009

N2 - The recent discovery that neurons call be photostimulated via genetic incorporation of artificial opsins is creating a revolution in the field of neural stimulation. In this paper we show its potential in the field of retinal prosthesis. We show that we need typically 100 mW cm(-2) in instantaneous light intensity on the neuron in order to stimulate action potentials. We also show how this can be reduced down to safe levels in order to negate thermal and photochromic damage to the eye. We also describe a gallium nitride LED light Source which is also able to generate patterns of the required intensity in order to transfer reliable images.

AB - The recent discovery that neurons call be photostimulated via genetic incorporation of artificial opsins is creating a revolution in the field of neural stimulation. In this paper we show its potential in the field of retinal prosthesis. We show that we need typically 100 mW cm(-2) in instantaneous light intensity on the neuron in order to stimulate action potentials. We also show how this can be reduced down to safe levels in order to negate thermal and photochromic damage to the eye. We also describe a gallium nitride LED light Source which is also able to generate patterns of the required intensity in order to transfer reliable images.

UR - http://www.scopus.com/inward/record.url?scp=68049135904&partnerID=8YFLogxK

M3 - Conference paper

VL - 6

JO - Journal Of Neural Engineering

JF - Journal Of Neural Engineering

IS - 3

M1 - 035007

T2 - Eye and the Chip Meeting 2008

Y2 - 12 June 2008 through 14 June 2008

ER -