Oral and genital lichenoid reactions associated with circulating autoantibodies to desmoplakins I and II: A novel target antigen or example of epitope spreading?

N Oyama; J F Setterfield; M J Gratian; B S Bhogal; P Shirlaw; S J Challacombe; M M Black

doi:10.1067/mjd.2003.198

Oral and genital lichenoid reactions associated with circulating autoantibodies to desmoplakins I and II: A novel target antigen or example of epitope spreading?

N Oyama
, J F Setterfield
, M J Gratian
, B S Bhogal
, P Shirlaw
, S J Challacombe
, M M Black

Research output: Contribution to journal › Article › peer-review

11 Citations (Scopus)

Abstract

We describe the first reported case of persistent Oral and genital lichenoid reactions associated with circulating antibodies to 250- and 215-kd proteins, compatible with desmoplakin I and 11, respectively. V-e discuss the potential role Of epitope spreading, leading to the novel development of specific autoantibodies to desmoplakin.

Original language	English
Pages (from-to)	433 - 438
Number of pages	6
Journal	Journal of the American Academy of Dermatology
Volume	48
Issue number	3
DOIs	https://doi.org/10.1067/mjd.2003.198
Publication status	Published - 1 Mar 2003

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10.1067/mjd.2003.198

Cite this

Oyama, N., Setterfield, J. F., Gratian, M. J., Bhogal, B. S., Shirlaw, P., Challacombe, S. J., & Black, M. M. (2003). Oral and genital lichenoid reactions associated with circulating autoantibodies to desmoplakins I and II: A novel target antigen or example of epitope spreading? Journal of the American Academy of Dermatology, 48(3), 433 - 438. https://doi.org/10.1067/mjd.2003.198

@article{67bc2a37e5d04b0c89f0063d8d8077bb,

title = "Oral and genital lichenoid reactions associated with circulating autoantibodies to desmoplakins I and II: A novel target antigen or example of epitope spreading?",

abstract = "We describe the first reported case of persistent Oral and genital lichenoid reactions associated with circulating antibodies to 250- and 215-kd proteins, compatible with desmoplakin I and 11, respectively. V-e discuss the potential role Of epitope spreading, leading to the novel development of specific autoantibodies to desmoplakin.",

author = "N Oyama and Setterfield, \{J F\} and Gratian, \{M J\} and Bhogal, \{B S\} and P Shirlaw and Challacombe, \{S J\} and Black, \{M M\}",

year = "2003",

month = mar,

day = "1",

doi = "10.1067/mjd.2003.198",

language = "English",

volume = "48",

pages = "433 -- 438",

journal = "Journal of the American Academy of Dermatology",

publisher = "Elsevier",

number = "3",

}