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Oral and genital lichenoid reactions associated with circulating autoantibodies to desmoplakins I and II: A novel target antigen or example of epitope spreading?

Research output: Contribution to journalArticle

N Oyama, J F Setterfield, M J Gratian, B S Bhogal, P Shirlaw, S J Challacombe, M M Black

Original languageEnglish
Pages (from-to)433 - 438
Number of pages6
JournalJournal of the American Academy of Dermatology
Volume48
Issue number3
DOIs
Publication statusPublished - 1 Mar 2003

King's Authors

Abstract

We describe the first reported case of persistent Oral and genital lichenoid reactions associated with circulating antibodies to 250- and 215-kd proteins, compatible with desmoplakin I and 11, respectively. V-e discuss the potential role Of epitope spreading, leading to the novel development of specific autoantibodies to desmoplakin.

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