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Oral submucous fibrosis: A historical perspective and a review on aetiology and pathogenesis

Research output: Contribution to journalArticle

Wanninayake Mudiyanselage Tilakaratne, Rasika Priyadharshani Ekanayaka, Kasturi Warnakulasuriya

Original languageEnglish
JournalOral Surgery Oral Medicine Oral Pathology Oral Radiology and Endodontics
Early online date19 Apr 2016
Accepted/In press4 Apr 2016
E-pub ahead of print19 Apr 2016


  • 1-s2.0-S2212440316300189-main

    1_s2.0_S2212440316300189_main.pdf, 982 KB, application/pdf

    Uploaded date:20 Apr 2016

    Version:Accepted author manuscript

    Licence:CC BY-NC-ND

King's Authors


Background Oral submucous fibrosis (OSF) is a chronic, insidious disease characterized by progressive submucosal fibrosis of the oral cavity and the oropharynx. People affected by this disease mostly live in south Asia, but migrants from these countries to the USA and Europe may present with OSF. Purpose We provide a historical background of the disease and the objective of this review is to update the current knowledge on the aetiology and aetiopathogenesis of OSF.

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