King's College London

Funding Information: We would like to thank the hepatology, surgical transplant and intensive care services at King’s College Hospital who went above and beyond to deal with this surge of patients with acute hepatitis. Funding Information: AkD is the Chair of Scientific Affairs of the European Society of Pediatric and Neonatal Intensive Care (ESPNIC). AnD is a recipient of a National Institute for Health Research (NIHR) i4i grant to develop treatment for ALF with alginate microbead embedded hepatocytes and a Medical Research Council (MRC) grant for a first in human clinical trial of alginate embedded human hepatocytes as treatment for ALF (MRC MR/V038583/1), has been paid by Ambys and J and J for consultation, has a patent pending approval for alginate microbead manufacturing. TG is a consultant for Albireo. None of the other authors declare any conflict of interest.