Outcome of a psychosocial health promotion intervention aimed at improving physical health and reducing alcohol use in patients with schizophrenia and psychotic disorders (MINT)

Jeanette Westman; Jonas Eberhard; Fiona P. Gaughran; Lennart Lundin; Richard Stenmark; Gunnar Edman; Sven V. Eriksson; Erik Jedenius; Pia Rydell; Karin Overgaard; Daniel Abrams; Kathryn E. Greenwood; Shubulade Smith; Khalida Ismail; Robin Murray; Urban Ösby

doi:10.1016/j.schres.2019.03.026

Outcome of a psychosocial health promotion intervention aimed at improving physical health and reducing alcohol use in patients with schizophrenia and psychotic disorders (MINT)

Jeanette Westman^*, Jonas Eberhard, Fiona P. Gaughran, Lennart Lundin, Richard Stenmark, Gunnar Edman, Sven V. Eriksson, Erik Jedenius, Pia Rydell, Karin Overgaard, Daniel Abrams, Kathryn E. Greenwood, Shubulade Smith, Khalida Ismail, Robin Murray, Urban Ösby

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

BACKGROUND: Life expectancy is reduced by 19 years in men and 17 in women with psychosis in Sweden, largely due to cardiovascular disease.

AIM: Assess whether a psychosocial health promotion intervention improves cardiometabolic risk factors, quality of life, and severity of illness in patients with psychotic disorders more than treatment as usual.

METHODS: A pragmatic intervention trial testing a manual-based multi-component health promotion intervention targeting patients with psychosis. The Swedish intervention was adapted from IMPaCT therapy, a health-promotion program based on motivational interviewing and cognitive behavioral therapy, designed to be incorporated into routine care. The intervention group consisted of 119 patients and the control group of 570 patients from specialized psychosis departments. Outcome variables were assessed 6 months before intervention during the run-in period, again at the start of intervention, and 12 months after the intervention began. The control group received treatment as usual.

RESULTS: The intervention had no significant effect on any of the outcome variables. However, BMI, waist circumference, systolic BP, heart rate, HbA1c, general health, and Clinical Global Impressions Scale score improved significantly during the run-in period before the start of the active intervention (observer effect). The multi-component design meant that treatment effects could only be calculated for the intervention as a whole.

CONCLUSION: The results of the intervention are similar to those of the U.K. IMPaCT study, in which the modular health-promotion intervention had little effect on cardiovascular risk indicators. However, in the current study, the run-in period had a positive effect on cardiometabolic risk factors.

Original language	English
Pages (from-to)	138-144
Number of pages	7
Journal	Schizophrenia Research
Volume	208
Early online date	9 Apr 2019
DOIs	https://doi.org/10.1016/j.schres.2019.03.026
Publication status	Published - Jun 2019

Keywords

Cardiovascular risk factors
Lifestyle intervention
Mental health
Psychiatric care
Psychosis
Run-in period

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.schres.2019.03.026

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Westman, J., Eberhard, J., Gaughran, F. P., Lundin, L., Stenmark, R., Edman, G., Eriksson, S. V., Jedenius, E., Rydell, P., Overgaard, K., Abrams, D., Greenwood, K. E., Smith, S., Ismail, K., Murray, R., & Ösby, U. (2019). Outcome of a psychosocial health promotion intervention aimed at improving physical health and reducing alcohol use in patients with schizophrenia and psychotic disorders (MINT). Schizophrenia Research, 208, 138-144. https://doi.org/10.1016/j.schres.2019.03.026

@article{c317d3820e0544fea0f44115d0107463,

title = "Outcome of a psychosocial health promotion intervention aimed at improving physical health and reducing alcohol use in patients with schizophrenia and psychotic disorders (MINT)",

abstract = "BACKGROUND: Life expectancy is reduced by 19 years in men and 17 in women with psychosis in Sweden, largely due to cardiovascular disease.AIM: Assess whether a psychosocial health promotion intervention improves cardiometabolic risk factors, quality of life, and severity of illness in patients with psychotic disorders more than treatment as usual.METHODS: A pragmatic intervention trial testing a manual-based multi-component health promotion intervention targeting patients with psychosis. The Swedish intervention was adapted from IMPaCT therapy, a health-promotion program based on motivational interviewing and cognitive behavioral therapy, designed to be incorporated into routine care. The intervention group consisted of 119 patients and the control group of 570 patients from specialized psychosis departments. Outcome variables were assessed 6 months before intervention during the run-in period, again at the start of intervention, and 12 months after the intervention began. The control group received treatment as usual.RESULTS: The intervention had no significant effect on any of the outcome variables. However, BMI, waist circumference, systolic BP, heart rate, HbA1c, general health, and Clinical Global Impressions Scale score improved significantly during the run-in period before the start of the active intervention (observer effect). The multi-component design meant that treatment effects could only be calculated for the intervention as a whole.CONCLUSION: The results of the intervention are similar to those of the U.K. IMPaCT study, in which the modular health-promotion intervention had little effect on cardiovascular risk indicators. However, in the current study, the run-in period had a positive effect on cardiometabolic risk factors.",

keywords = "Cardiovascular risk factors, Lifestyle intervention, Mental health, Psychiatric care, Psychosis, Run-in period",

author = "Jeanette Westman and Jonas Eberhard and Gaughran, {Fiona P.} and Lennart Lundin and Richard Stenmark and Gunnar Edman and Eriksson, {Sven V.} and Erik Jedenius and Pia Rydell and Karin Overgaard and Daniel Abrams and Greenwood, {Kathryn E.} and Shubulade Smith and Khalida Ismail and Robin Murray and Urban {\"O}sby",

note = "Copyright {\textcopyright} 2019. Published by Elsevier B.V.",

year = "2019",

month = jun,

doi = "10.1016/j.schres.2019.03.026",

language = "English",

volume = "208",

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Westman, J, Eberhard, J, Gaughran, FP, Lundin, L, Stenmark, R, Edman, G, Eriksson, SV, Jedenius, E, Rydell, P, Overgaard, K, Abrams, D, Greenwood, KE, Smith, S , Ismail, K , Murray, R & Ösby, U 2019, 'Outcome of a psychosocial health promotion intervention aimed at improving physical health and reducing alcohol use in patients with schizophrenia and psychotic disorders (MINT)', Schizophrenia Research, vol. 208, pp. 138-144. https://doi.org/10.1016/j.schres.2019.03.026

TY - JOUR

T1 - Outcome of a psychosocial health promotion intervention aimed at improving physical health and reducing alcohol use in patients with schizophrenia and psychotic disorders (MINT)

AU - Westman, Jeanette

AU - Eberhard, Jonas

AU - Gaughran, Fiona P.

AU - Lundin, Lennart

AU - Stenmark, Richard

AU - Edman, Gunnar

AU - Eriksson, Sven V.

AU - Jedenius, Erik

AU - Rydell, Pia

AU - Overgaard, Karin

AU - Abrams, Daniel

AU - Greenwood, Kathryn E.

AU - Smith, Shubulade

AU - Ismail, Khalida

AU - Murray, Robin

AU - Ösby, Urban

PY - 2019/6

Y1 - 2019/6

N2 - BACKGROUND: Life expectancy is reduced by 19 years in men and 17 in women with psychosis in Sweden, largely due to cardiovascular disease.AIM: Assess whether a psychosocial health promotion intervention improves cardiometabolic risk factors, quality of life, and severity of illness in patients with psychotic disorders more than treatment as usual.METHODS: A pragmatic intervention trial testing a manual-based multi-component health promotion intervention targeting patients with psychosis. The Swedish intervention was adapted from IMPaCT therapy, a health-promotion program based on motivational interviewing and cognitive behavioral therapy, designed to be incorporated into routine care. The intervention group consisted of 119 patients and the control group of 570 patients from specialized psychosis departments. Outcome variables were assessed 6 months before intervention during the run-in period, again at the start of intervention, and 12 months after the intervention began. The control group received treatment as usual.RESULTS: The intervention had no significant effect on any of the outcome variables. However, BMI, waist circumference, systolic BP, heart rate, HbA1c, general health, and Clinical Global Impressions Scale score improved significantly during the run-in period before the start of the active intervention (observer effect). The multi-component design meant that treatment effects could only be calculated for the intervention as a whole.CONCLUSION: The results of the intervention are similar to those of the U.K. IMPaCT study, in which the modular health-promotion intervention had little effect on cardiovascular risk indicators. However, in the current study, the run-in period had a positive effect on cardiometabolic risk factors.

AB - BACKGROUND: Life expectancy is reduced by 19 years in men and 17 in women with psychosis in Sweden, largely due to cardiovascular disease.AIM: Assess whether a psychosocial health promotion intervention improves cardiometabolic risk factors, quality of life, and severity of illness in patients with psychotic disorders more than treatment as usual.METHODS: A pragmatic intervention trial testing a manual-based multi-component health promotion intervention targeting patients with psychosis. The Swedish intervention was adapted from IMPaCT therapy, a health-promotion program based on motivational interviewing and cognitive behavioral therapy, designed to be incorporated into routine care. The intervention group consisted of 119 patients and the control group of 570 patients from specialized psychosis departments. Outcome variables were assessed 6 months before intervention during the run-in period, again at the start of intervention, and 12 months after the intervention began. The control group received treatment as usual.RESULTS: The intervention had no significant effect on any of the outcome variables. However, BMI, waist circumference, systolic BP, heart rate, HbA1c, general health, and Clinical Global Impressions Scale score improved significantly during the run-in period before the start of the active intervention (observer effect). The multi-component design meant that treatment effects could only be calculated for the intervention as a whole.CONCLUSION: The results of the intervention are similar to those of the U.K. IMPaCT study, in which the modular health-promotion intervention had little effect on cardiovascular risk indicators. However, in the current study, the run-in period had a positive effect on cardiometabolic risk factors.

KW - Cardiovascular risk factors

KW - Lifestyle intervention

KW - Mental health

KW - Psychiatric care

KW - Psychosis

KW - Run-in period

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DO - 10.1016/j.schres.2019.03.026

M3 - Article

C2 - 30979666

AN - SCOPUS:85064003950

SN - 0920-9964

VL - 208

SP - 138

EP - 144

JO - Schizophrenia Research

JF - Schizophrenia Research

ER -

Outcome of a psychosocial health promotion intervention aimed at improving physical health and reducing alcohol use in patients with schizophrenia and psychotic disorders (MINT)

Abstract

Keywords

UN SDGs

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