Painless foot drop: An unusual acute presentation of new onset type 1 diabetes mellitus

Antonella Corcillo*, Zoe Kleinaki, Stella Kapnisi, Nikolaos Fountoulakis, Giuseppe Maltese, Stephen M. Thomas, Janaka Karalliedde

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)


A 26-year-old Caucasian female with no past medical history or family history of auto-immune disease presented to the emergency department with new onset painless left foot drop. A panel of blood tests revealed blood glucose of 49.9 mmol/L and raised blood ketone levels. The patient was referred to the diabetes team who made a clinical diagnosis of type 1 diabetes (T1DM) and insulin treatment was initiated. Elevated levels of diabetes auto-antibodies were subsequently detected. Nerve conduction studies demonstrated a left common peroneal nerve lesion with conduction block at the fibular head. After 2 weeks of insulin treatment, a significant improvement of her foot drop was observed and after 8 weeks she was walking normally. The most probable cause of her foot drop was acute diabetic mononeuropathy. To our knowledge, there are no similar cases in adult patients reported in the literature. Our case highlights the importance of physicians being aware of atypical presentation of new onset T1DM.

Original languageEnglish
Article number21-0012
JournalEndocrinology, Diabetes and Metabolism Case Reports
Issue number1
Publication statusPublished - 2021


Dive into the research topics of 'Painless foot drop: An unusual acute presentation of new onset type 1 diabetes mellitus'. Together they form a unique fingerprint.

Cite this