Abstract
OBJECTIVE:
To investigate the parental physical and lifestyle determinants of newborn body composition.
DESIGN:
Prospective cohort study.
SETTING:
Cork University Maternity Hospital, a tertiary referral hospital in Cork, Ireland.
POPULATION:
All babies were recruited as part of a prospective birth cohort, Babies After
SCOPE:
Evaluating the Longitudinal Impact Using Neurological and Nutritional Endpoints (BASELINE). These babies were recruited from women who had participated in the Screening of Pregnancy Endpoints (SCOPE) study Ireland, a prospective, multicentre cohort study
METHODS:
Multivariate linear regression was used to analyse the effect of a range of maternal and paternal physical and lifestyle features on neonatal body fat percentage (BF%).
MAIN OUTCOME MEASURES:
Neonatal BF%. Neonatal adiposity was assessed within 48 hours of birth using air displacement plethysmography (PEAPOD(®) ).
RESULTS:
In all, 1243 infants were enrolled in the study. Increasing maternal body mass index (adjusted mean difference 0.09; 0.04, 0.15) and waist height ratio (adjusted mean difference 6.59; 0.27, 12.92) were significantly associated with increased neonatal BF%. In contrast, maternal smoking was associated with reduced neonatal BF% compared with non smokers (adjusted mean difference -0.55; -1.07, -0.03). Infant sex significantly altered neonatal BF%, with female infants having higher neonatal BF% compared with male infants (adjusted mean difference 1.98; 1.54, 2.53). No association was observed between paternal body mass index (BMI), paternal age or paternal smoking and neonatal BF%.
CONCLUSIONS:
Maternal smoking, BMI, waist height ratio and infant sex were associated with altered BF%.
TWEETABLE ABSTRACT:
Maternal smoking, BMI, waist height ratio and infant sex are associated with altered neonatal body fat percentage.
© 2016 Royal College of Obstetricians and Gynaecologists.
To investigate the parental physical and lifestyle determinants of newborn body composition.
DESIGN:
Prospective cohort study.
SETTING:
Cork University Maternity Hospital, a tertiary referral hospital in Cork, Ireland.
POPULATION:
All babies were recruited as part of a prospective birth cohort, Babies After
SCOPE:
Evaluating the Longitudinal Impact Using Neurological and Nutritional Endpoints (BASELINE). These babies were recruited from women who had participated in the Screening of Pregnancy Endpoints (SCOPE) study Ireland, a prospective, multicentre cohort study
METHODS:
Multivariate linear regression was used to analyse the effect of a range of maternal and paternal physical and lifestyle features on neonatal body fat percentage (BF%).
MAIN OUTCOME MEASURES:
Neonatal BF%. Neonatal adiposity was assessed within 48 hours of birth using air displacement plethysmography (PEAPOD(®) ).
RESULTS:
In all, 1243 infants were enrolled in the study. Increasing maternal body mass index (adjusted mean difference 0.09; 0.04, 0.15) and waist height ratio (adjusted mean difference 6.59; 0.27, 12.92) were significantly associated with increased neonatal BF%. In contrast, maternal smoking was associated with reduced neonatal BF% compared with non smokers (adjusted mean difference -0.55; -1.07, -0.03). Infant sex significantly altered neonatal BF%, with female infants having higher neonatal BF% compared with male infants (adjusted mean difference 1.98; 1.54, 2.53). No association was observed between paternal body mass index (BMI), paternal age or paternal smoking and neonatal BF%.
CONCLUSIONS:
Maternal smoking, BMI, waist height ratio and infant sex were associated with altered BF%.
TWEETABLE ABSTRACT:
Maternal smoking, BMI, waist height ratio and infant sex are associated with altered neonatal body fat percentage.
© 2016 Royal College of Obstetricians and Gynaecologists.
| Original language | English |
|---|---|
| Article number | DOI: 10.1111/1471-0528.14042 |
| Pages (from-to) | 1824 |
| Journal | BJOG |
| Volume | 123 |
| Issue number | 11 |
| Publication status | Published - Oct 2016 |