King's College London

Research portal

Pathophysiology of AKI

Research output: Contribution to journalArticlepeer-review

Standard

Pathophysiology of AKI. / Ostermann, Marlies; Liu, Kathleen.

In: Bailliere's Best Practice in Clinical Anaesthesiology, 22.09.2017.

Research output: Contribution to journalArticlepeer-review

Harvard

Ostermann, M & Liu, K 2017, 'Pathophysiology of AKI', Bailliere's Best Practice in Clinical Anaesthesiology. https://doi.org/10.1016/j.bpa.2017.09.001

APA

Ostermann, M., & Liu, K. (2017). Pathophysiology of AKI. Bailliere's Best Practice in Clinical Anaesthesiology. https://doi.org/10.1016/j.bpa.2017.09.001

Vancouver

Ostermann M, Liu K. Pathophysiology of AKI. Bailliere's Best Practice in Clinical Anaesthesiology. 2017 Sep 22. https://doi.org/10.1016/j.bpa.2017.09.001

Author

Ostermann, Marlies ; Liu, Kathleen. / Pathophysiology of AKI. In: Bailliere's Best Practice in Clinical Anaesthesiology. 2017.

Bibtex Download

@article{60c0335176d04264aa51869481fd2d09,
title = "Pathophysiology of AKI",
abstract = "Acute kidney injury (AKI) is common in the perioperative and intensive care setting. Although AKI is usually multifactorial, haemodynamic instability, sepsis and drug toxicity are commonly implicated. Independent of the exact aetiology, several different pathophysiologic processes occur simultaneously and in sequence, including endothelial dysfunction, alteration of the microcirculation, tubular injury, venous congestion and intrarenal inflammation. A multitude of different immune cells from within the kidney and the systemic circulation play a role in the development, maintenance and recovery phase of AKI. In this review we describe the common processes involved in AKI and their connections with particular emphasis on the perioperative and critical care setting.",
keywords = "acute kidney injury, pathophysiology, inflammation, endothelial dysfunction, tubular injury, microcirculation",
author = "Marlies Ostermann and Kathleen Liu",
year = "2017",
month = sep,
day = "22",
doi = "10.1016/j.bpa.2017.09.001",
language = "English",
journal = "Bailliere's Best Practice in Clinical Anaesthesiology",
issn = "1521-6896",
publisher = "Bailliere Tindall Ltd",

}

RIS (suitable for import to EndNote) Download

TY - JOUR

T1 - Pathophysiology of AKI

AU - Ostermann, Marlies

AU - Liu, Kathleen

PY - 2017/9/22

Y1 - 2017/9/22

N2 - Acute kidney injury (AKI) is common in the perioperative and intensive care setting. Although AKI is usually multifactorial, haemodynamic instability, sepsis and drug toxicity are commonly implicated. Independent of the exact aetiology, several different pathophysiologic processes occur simultaneously and in sequence, including endothelial dysfunction, alteration of the microcirculation, tubular injury, venous congestion and intrarenal inflammation. A multitude of different immune cells from within the kidney and the systemic circulation play a role in the development, maintenance and recovery phase of AKI. In this review we describe the common processes involved in AKI and their connections with particular emphasis on the perioperative and critical care setting.

AB - Acute kidney injury (AKI) is common in the perioperative and intensive care setting. Although AKI is usually multifactorial, haemodynamic instability, sepsis and drug toxicity are commonly implicated. Independent of the exact aetiology, several different pathophysiologic processes occur simultaneously and in sequence, including endothelial dysfunction, alteration of the microcirculation, tubular injury, venous congestion and intrarenal inflammation. A multitude of different immune cells from within the kidney and the systemic circulation play a role in the development, maintenance and recovery phase of AKI. In this review we describe the common processes involved in AKI and their connections with particular emphasis on the perioperative and critical care setting.

KW - acute kidney injury

KW - pathophysiology

KW - inflammation

KW - endothelial dysfunction

KW - tubular injury

KW - microcirculation

U2 - 10.1016/j.bpa.2017.09.001

DO - 10.1016/j.bpa.2017.09.001

M3 - Article

JO - Bailliere's Best Practice in Clinical Anaesthesiology

JF - Bailliere's Best Practice in Clinical Anaesthesiology

SN - 1521-6896

ER -

View graph of relations

© 2020 King's College London | Strand | London WC2R 2LS | England | United Kingdom | Tel +44 (0)20 7836 5454