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Patient outcomes up to 15 years after stroke: Survival, disability, quality of life, cognition and mental health

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Patient outcomes up to 15 years after stroke : Survival, disability, quality of life, cognition and mental health. / Crichton, Siobhan Laura; Bray, Benjamin David; McKevitt, Christopher John; Rudd, Anthony G.; Wolfe, Charles David Alexander.

In: Journal of Neurology, Neurosurgery and Psychiatry, Vol. 87, No. 10, 01.10.2016, p. 1091-1098.

Research output: Contribution to journalArticle

Harvard

Crichton, SL, Bray, BD, McKevitt, CJ, Rudd, AG & Wolfe, CDA 2016, 'Patient outcomes up to 15 years after stroke: Survival, disability, quality of life, cognition and mental health', Journal of Neurology, Neurosurgery and Psychiatry, vol. 87, no. 10, pp. 1091-1098. https://doi.org/10.1136/jnnp-2016-313361

APA

Crichton, S. L., Bray, B. D., McKevitt, C. J., Rudd, A. G., & Wolfe, C. D. A. (2016). Patient outcomes up to 15 years after stroke: Survival, disability, quality of life, cognition and mental health. Journal of Neurology, Neurosurgery and Psychiatry, 87(10), 1091-1098. https://doi.org/10.1136/jnnp-2016-313361

Vancouver

Crichton SL, Bray BD, McKevitt CJ, Rudd AG, Wolfe CDA. Patient outcomes up to 15 years after stroke: Survival, disability, quality of life, cognition and mental health. Journal of Neurology, Neurosurgery and Psychiatry. 2016 Oct 1;87(10):1091-1098. https://doi.org/10.1136/jnnp-2016-313361

Author

Crichton, Siobhan Laura ; Bray, Benjamin David ; McKevitt, Christopher John ; Rudd, Anthony G. ; Wolfe, Charles David Alexander. / Patient outcomes up to 15 years after stroke : Survival, disability, quality of life, cognition and mental health. In: Journal of Neurology, Neurosurgery and Psychiatry. 2016 ; Vol. 87, No. 10. pp. 1091-1098.

Bibtex Download

@article{c91f7565c2e54580bc50ec3a13c65285,
title = "Patient outcomes up to 15 years after stroke: Survival, disability, quality of life, cognition and mental health",
abstract = "Background: The global epidemiological shift of disease burden towards long term conditions means understanding long-term outcomes of cardiovascular disease is increasingly important. More people are surviving stroke to experience it's long term consequences, but outcomes in people living more >10 years after stroke have not been described in detail. Methods:Data were collected for the population-based South London Stroke Register, with participants followed up annually until death. Outcomes were survival, disability, activity, cognitive impairment, quality of life, depression and anxiety. FindingsOf 2625 people having first-ever stroke, 262(21{\%}) survived to 15 years. By 15 years, 61{\%}(95{\%} CI 55- 67{\%}) of the survivors were male, with a median age of stroke onset of 58 years (IQR 48-66). 87{\%} of the 15 year survivors were living at home and 33.8{\%}(26.2-42.4{\%}) had mild disability, 14.3{\%} (9.2-21.4{\%}) moderate disability and 15.0{\%}(9.9-22.3{\%}) severe disability. The prevalence of disability increased with time but one in ten of the 15 year survivors had lived with moderate-severe disability since their stroke. At 15 years, the prevalence of cognitive impairment was 30.0{\%}(19.5-43.1{\%}), depression 39.1{\%}(30.9-47.9{\%}) and anxiety 34.9{\%}(27.0-43.8{\%}) and survivors reported greater loss of physical than mental quality of life. Conclusions:One in five people live at least 15 years after a stroke and poor functional, cognitive and psychological outcomes affect a substantial proportion of these long term survivors. As the global population of individuals with cardiovascular long term conditions grows, research and health services will need to increasingly focus on preventing and managing the long term consequences of stroke.",
author = "Crichton, {Siobhan Laura} and Bray, {Benjamin David} and McKevitt, {Christopher John} and Rudd, {Anthony G.} and Wolfe, {Charles David Alexander}",
year = "2016",
month = "10",
day = "1",
doi = "10.1136/jnnp-2016-313361",
language = "English",
volume = "87",
pages = "1091--1098",
journal = "Journal of Neurology, Neurosurgery and Psychiatry",
issn = "0022-3050",
publisher = "BMJ Publishing Group",
number = "10",

}

RIS (suitable for import to EndNote) Download

TY - JOUR

T1 - Patient outcomes up to 15 years after stroke

T2 - Survival, disability, quality of life, cognition and mental health

AU - Crichton, Siobhan Laura

AU - Bray, Benjamin David

AU - McKevitt, Christopher John

AU - Rudd, Anthony G.

AU - Wolfe, Charles David Alexander

PY - 2016/10/1

Y1 - 2016/10/1

N2 - Background: The global epidemiological shift of disease burden towards long term conditions means understanding long-term outcomes of cardiovascular disease is increasingly important. More people are surviving stroke to experience it's long term consequences, but outcomes in people living more >10 years after stroke have not been described in detail. Methods:Data were collected for the population-based South London Stroke Register, with participants followed up annually until death. Outcomes were survival, disability, activity, cognitive impairment, quality of life, depression and anxiety. FindingsOf 2625 people having first-ever stroke, 262(21%) survived to 15 years. By 15 years, 61%(95% CI 55- 67%) of the survivors were male, with a median age of stroke onset of 58 years (IQR 48-66). 87% of the 15 year survivors were living at home and 33.8%(26.2-42.4%) had mild disability, 14.3% (9.2-21.4%) moderate disability and 15.0%(9.9-22.3%) severe disability. The prevalence of disability increased with time but one in ten of the 15 year survivors had lived with moderate-severe disability since their stroke. At 15 years, the prevalence of cognitive impairment was 30.0%(19.5-43.1%), depression 39.1%(30.9-47.9%) and anxiety 34.9%(27.0-43.8%) and survivors reported greater loss of physical than mental quality of life. Conclusions:One in five people live at least 15 years after a stroke and poor functional, cognitive and psychological outcomes affect a substantial proportion of these long term survivors. As the global population of individuals with cardiovascular long term conditions grows, research and health services will need to increasingly focus on preventing and managing the long term consequences of stroke.

AB - Background: The global epidemiological shift of disease burden towards long term conditions means understanding long-term outcomes of cardiovascular disease is increasingly important. More people are surviving stroke to experience it's long term consequences, but outcomes in people living more >10 years after stroke have not been described in detail. Methods:Data were collected for the population-based South London Stroke Register, with participants followed up annually until death. Outcomes were survival, disability, activity, cognitive impairment, quality of life, depression and anxiety. FindingsOf 2625 people having first-ever stroke, 262(21%) survived to 15 years. By 15 years, 61%(95% CI 55- 67%) of the survivors were male, with a median age of stroke onset of 58 years (IQR 48-66). 87% of the 15 year survivors were living at home and 33.8%(26.2-42.4%) had mild disability, 14.3% (9.2-21.4%) moderate disability and 15.0%(9.9-22.3%) severe disability. The prevalence of disability increased with time but one in ten of the 15 year survivors had lived with moderate-severe disability since their stroke. At 15 years, the prevalence of cognitive impairment was 30.0%(19.5-43.1%), depression 39.1%(30.9-47.9%) and anxiety 34.9%(27.0-43.8%) and survivors reported greater loss of physical than mental quality of life. Conclusions:One in five people live at least 15 years after a stroke and poor functional, cognitive and psychological outcomes affect a substantial proportion of these long term survivors. As the global population of individuals with cardiovascular long term conditions grows, research and health services will need to increasingly focus on preventing and managing the long term consequences of stroke.

UR - http://www.scopus.com/inward/record.url?scp=84978942629&partnerID=8YFLogxK

U2 - 10.1136/jnnp-2016-313361

DO - 10.1136/jnnp-2016-313361

M3 - Article

VL - 87

SP - 1091

EP - 1098

JO - Journal of Neurology, Neurosurgery and Psychiatry

JF - Journal of Neurology, Neurosurgery and Psychiatry

SN - 0022-3050

IS - 10

ER -

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