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Patient-specific polyvinyl alcohol phantom fabrication with ultrasound and x-ray contrast for brain tumor surgery planning

Research output: Contribution to journalArticle

Standard

Patient-specific polyvinyl alcohol phantom fabrication with ultrasound and x-ray contrast for brain tumor surgery planning. / Mackle, Eleanor C.; Shapey, Jonathan; Maneas, Efthymios; Saeed, Shakeel R.; Bradford, Robert; Ourselin, Sebastien; Vercauteren, Tom; Desjardins, Adrien E.

In: Journal of Visualized Experiments, Vol. 2020, No. 161, e61344, 07.2020, p. 1-18.

Research output: Contribution to journalArticle

Harvard

Mackle, EC, Shapey, J, Maneas, E, Saeed, SR, Bradford, R, Ourselin, S, Vercauteren, T & Desjardins, AE 2020, 'Patient-specific polyvinyl alcohol phantom fabrication with ultrasound and x-ray contrast for brain tumor surgery planning', Journal of Visualized Experiments, vol. 2020, no. 161, e61344, pp. 1-18. https://doi.org/10.3791/61344

APA

Mackle, E. C., Shapey, J., Maneas, E., Saeed, S. R., Bradford, R., Ourselin, S., Vercauteren, T., & Desjardins, A. E. (2020). Patient-specific polyvinyl alcohol phantom fabrication with ultrasound and x-ray contrast for brain tumor surgery planning. Journal of Visualized Experiments, 2020(161), 1-18. [e61344]. https://doi.org/10.3791/61344

Vancouver

Mackle EC, Shapey J, Maneas E, Saeed SR, Bradford R, Ourselin S et al. Patient-specific polyvinyl alcohol phantom fabrication with ultrasound and x-ray contrast for brain tumor surgery planning. Journal of Visualized Experiments. 2020 Jul;2020(161):1-18. e61344. https://doi.org/10.3791/61344

Author

Mackle, Eleanor C. ; Shapey, Jonathan ; Maneas, Efthymios ; Saeed, Shakeel R. ; Bradford, Robert ; Ourselin, Sebastien ; Vercauteren, Tom ; Desjardins, Adrien E. / Patient-specific polyvinyl alcohol phantom fabrication with ultrasound and x-ray contrast for brain tumor surgery planning. In: Journal of Visualized Experiments. 2020 ; Vol. 2020, No. 161. pp. 1-18.

Bibtex Download

@article{0b9c88657f7940e3a2ca909c08bca338,
title = "Patient-specific polyvinyl alcohol phantom fabrication with ultrasound and x-ray contrast for brain tumor surgery planning",
abstract = "Phantoms are essential tools for clinical training, surgical planning and the development of novel medical devices. However, it is challenging to create anatomically accurate head phantoms with realistic brain imaging properties because standard fabrication methods are not optimized to replicate any patient-specific anatomical detail and 3D printing materials are not optimized for imaging properties. In order to test and validate a novel navigation system for use during brain tumor surgery, an anatomically accurate phantom with realistic imaging and mechanical properties was required. Therefore, a phantom was developed using real patient data as input and 3D printing of molds to fabricate a patient-specific head phantom comprising the skull, brain and tumor with both ultrasound and X-ray contrast. The phantom also had mechanical properties that allowed the phantom tissue to be manipulated in a similar manner to how human brain tissue is handled during surgery. The phantom was successfully tested during a surgical simulation in a virtual operating room. The phantom fabrication method uses commercially available materials and is easy to reproduce. The 3D printing files can be readily shared, and the technique can be adapted to encompass many different types of tumor.",
author = "Mackle, {Eleanor C.} and Jonathan Shapey and Efthymios Maneas and Saeed, {Shakeel R.} and Robert Bradford and Sebastien Ourselin and Tom Vercauteren and Desjardins, {Adrien E.}",
year = "2020",
month = jul,
doi = "10.3791/61344",
language = "English",
volume = "2020",
pages = "1--18",
journal = "Journal of Visualized Experiments",
issn = "1940-087X",
publisher = "MYJoVE Corporation",
number = "161",

}

RIS (suitable for import to EndNote) Download

TY - JOUR

T1 - Patient-specific polyvinyl alcohol phantom fabrication with ultrasound and x-ray contrast for brain tumor surgery planning

AU - Mackle, Eleanor C.

AU - Shapey, Jonathan

AU - Maneas, Efthymios

AU - Saeed, Shakeel R.

AU - Bradford, Robert

AU - Ourselin, Sebastien

AU - Vercauteren, Tom

AU - Desjardins, Adrien E.

PY - 2020/7

Y1 - 2020/7

N2 - Phantoms are essential tools for clinical training, surgical planning and the development of novel medical devices. However, it is challenging to create anatomically accurate head phantoms with realistic brain imaging properties because standard fabrication methods are not optimized to replicate any patient-specific anatomical detail and 3D printing materials are not optimized for imaging properties. In order to test and validate a novel navigation system for use during brain tumor surgery, an anatomically accurate phantom with realistic imaging and mechanical properties was required. Therefore, a phantom was developed using real patient data as input and 3D printing of molds to fabricate a patient-specific head phantom comprising the skull, brain and tumor with both ultrasound and X-ray contrast. The phantom also had mechanical properties that allowed the phantom tissue to be manipulated in a similar manner to how human brain tissue is handled during surgery. The phantom was successfully tested during a surgical simulation in a virtual operating room. The phantom fabrication method uses commercially available materials and is easy to reproduce. The 3D printing files can be readily shared, and the technique can be adapted to encompass many different types of tumor.

AB - Phantoms are essential tools for clinical training, surgical planning and the development of novel medical devices. However, it is challenging to create anatomically accurate head phantoms with realistic brain imaging properties because standard fabrication methods are not optimized to replicate any patient-specific anatomical detail and 3D printing materials are not optimized for imaging properties. In order to test and validate a novel navigation system for use during brain tumor surgery, an anatomically accurate phantom with realistic imaging and mechanical properties was required. Therefore, a phantom was developed using real patient data as input and 3D printing of molds to fabricate a patient-specific head phantom comprising the skull, brain and tumor with both ultrasound and X-ray contrast. The phantom also had mechanical properties that allowed the phantom tissue to be manipulated in a similar manner to how human brain tissue is handled during surgery. The phantom was successfully tested during a surgical simulation in a virtual operating room. The phantom fabrication method uses commercially available materials and is easy to reproduce. The 3D printing files can be readily shared, and the technique can be adapted to encompass many different types of tumor.

UR - http://www.scopus.com/inward/record.url?scp=85088575786&partnerID=8YFLogxK

U2 - 10.3791/61344

DO - 10.3791/61344

M3 - Article

C2 - 32744524

AN - SCOPUS:85088575786

VL - 2020

SP - 1

EP - 18

JO - Journal of Visualized Experiments

JF - Journal of Visualized Experiments

SN - 1940-087X

IS - 161

M1 - e61344

ER -

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