PCOS remains a diagnosis of exclusion: a concise review of key endocrinopathies to exclude

Eleni Magdalini Kyritsi; Georgios K Dimitriadis; Ioannis Kyrou; Gregory Kaltsas; Harpal S Randeva

doi:10.1111/cen.13245

PCOS remains a diagnosis of exclusion: a concise review of key endocrinopathies to exclude

Eleni Magdalini Kyritsi, Georgios K Dimitriadis, Ioannis Kyrou, Gregory Kaltsas, Harpal S Randeva

Diabetes

Renal Medicine and Transplantation, University Hospitals Coventry and Warwickshire NHS Trust, Coventry, United Kingdom.

Research output: Contribution to journal › Review article › peer-review

27 Citations (Scopus)

Abstract

Polycystic ovarian syndrome (PCOS) is a heterogenous disorder associated with clinical, endocrine and ultrasonographic features that can also be encountered in a number of other diseases. It has traditionally been suggested that prolactin excess, enzymatic steroidogenic abnormalities and thyroid disorders need to be excluded before a diagnosis of PCOS is made. However, there is paucity of data regarding the prevalence of PCOS phenotype in some of these disorders, whereas other endocrine diseases that exhibit PCOS-like features may elude diagnosis and proper management if not considered. This article reviews the data of currently included entities that exhibit a PCOS phenotype and those that potentially need to be looked for, and attempts to identify specific features that distinguish them from idiopathic PCOS.

Original language	English
Pages (from-to)	1-6
Number of pages	6
Journal	Clinical endocrinology
Volume	86
Issue number	1
DOIs	https://doi.org/10.1111/cen.13245
Publication status	Published - 1 Jan 2017

Keywords

Diagnosis, Differential
Female
Humans
Polycystic Ovary Syndrome/diagnosis

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abstract = "Polycystic ovarian syndrome (PCOS) is a heterogenous disorder associated with clinical, endocrine and ultrasonographic features that can also be encountered in a number of other diseases. It has traditionally been suggested that prolactin excess, enzymatic steroidogenic abnormalities and thyroid disorders need to be excluded before a diagnosis of PCOS is made. However, there is paucity of data regarding the prevalence of PCOS phenotype in some of these disorders, whereas other endocrine diseases that exhibit PCOS-like features may elude diagnosis and proper management if not considered. This article reviews the data of currently included entities that exhibit a PCOS phenotype and those that potentially need to be looked for, and attempts to identify specific features that distinguish them from idiopathic PCOS.",

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AU - Dimitriadis, Georgios K

AU - Kyrou, Ioannis

AU - Kaltsas, Gregory

AU - Randeva, Harpal S

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PCOS remains a diagnosis of exclusion: a concise review of key endocrinopathies to exclude

Abstract

Keywords

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