Percutaneous radiofrequency ablation of small renal tumours in patients with a single functioning kidney: long-term results

Miltiadis Krokidis; Stavros Spiliopoulos; Magdalena Jarzabek; Nikos Fotiadis; Tarun Sabharwal; Tim O'Brien; Andy Adam

doi:10.1007/s00330-013-2802-5

Percutaneous radiofrequency ablation of small renal tumours in patients with a single functioning kidney: long-term results

Miltiadis Krokidis^*, Stavros Spiliopoulos, Magdalena Jarzabek, Nikos Fotiadis, Tarun Sabharwal, Tim O'Brien , Andy Adam

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

15 Citations (Scopus)

Abstract

Objectives
To evaluate the long-term results of percutaneous radiofrequency ablation (RFA) of small renal tumours in patients with a single functioning kidney (SFK).

Methods
This is a single-centre prospective study. Patients with an SFK and a tumour smaller than 3.5 cm, treated with RFA over a 7.5-year period, were included. Nineteen consecutive patients (12 male), aged between 33 and 83 years (mean 61.4), were treated for 23 lesions. Primary endpoints were technical success and tumour recurrence rate. Secondary endpoints were the deterioration of renal function and overall survival rate.

Results
The mean follow-up was 56.1 months (range 36-102). Primary technical success was 100 %. There were no major peri-procedural complications. In two cases, minor complications occurred. There was no significant difference between the baseline glomerular filtration rate (GFR) and GFR at 3, 12 and 24 months post-procedure. In four lesions (17 %), recurrence was detected and an additional RFA session was performed. None of the patients developed renal failure during their lifetime. Three of the patients died because of other reasons.

Conclusions
Percutaneous RFA of small renal tumours in patients with an SFK offers very satisfactory long-term results regarding preservation of renal function, local tumour control and overall survival.

Key Points
Tumour in a single functioning kidney requires minimally invasive treatment.

Radiofrequency ablation plays an established role in managing small renal tumours.

Long-term results of radiofrequency ablation have shown satisfactory local tumour control.

Long-term results have also shown that renal function may be preserved.

Original language	English
Pages (from-to)	1933-1939
Number of pages	7
Journal	European Radiology
Volume	23
Issue number	7
DOIs	https://doi.org/10.1007/s00330-013-2802-5
Publication status	Published - Jul 2013

Keywords

Renal cancer
Nephrons
Radiofrequency catheter ablation
Ablation techniques
Nephrectomy
SOLITARY KIDNEY
CELL CARCINOMA
ETHANOL INJECTION
OUTCOMES
MASSES
CRYOABLATION
EXPERIENCE
FEATURES
CANCER
VIVO

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1007/s00330-013-2802-5

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@article{086a3a5d0cdf4e88ae365e98c87d472b,

title = "Percutaneous radiofrequency ablation of small renal tumours in patients with a single functioning kidney: long-term results",

abstract = "Objectives To evaluate the long-term results of percutaneous radiofrequency ablation (RFA) of small renal tumours in patients with a single functioning kidney (SFK). Methods This is a single-centre prospective study. Patients with an SFK and a tumour smaller than 3.5 cm, treated with RFA over a 7.5-year period, were included. Nineteen consecutive patients (12 male), aged between 33 and 83 years (mean 61.4), were treated for 23 lesions. Primary endpoints were technical success and tumour recurrence rate. Secondary endpoints were the deterioration of renal function and overall survival rate. Results The mean follow-up was 56.1 months (range 36-102). Primary technical success was 100 %. There were no major peri-procedural complications. In two cases, minor complications occurred. There was no significant difference between the baseline glomerular filtration rate (GFR) and GFR at 3, 12 and 24 months post-procedure. In four lesions (17 %), recurrence was detected and an additional RFA session was performed. None of the patients developed renal failure during their lifetime. Three of the patients died because of other reasons. Conclusions Percutaneous RFA of small renal tumours in patients with an SFK offers very satisfactory long-term results regarding preservation of renal function, local tumour control and overall survival. Key Points Tumour in a single functioning kidney requires minimally invasive treatment. Radiofrequency ablation plays an established role in managing small renal tumours. Long-term results of radiofrequency ablation have shown satisfactory local tumour control. Long-term results have also shown that renal function may be preserved.",

keywords = "Renal cancer, Nephrons, Radiofrequency catheter ablation, Ablation techniques, Nephrectomy, SOLITARY KIDNEY, CELL CARCINOMA, ETHANOL INJECTION, OUTCOMES, MASSES, CRYOABLATION, EXPERIENCE, FEATURES, CANCER, VIVO",

author = "Miltiadis Krokidis and Stavros Spiliopoulos and Magdalena Jarzabek and Nikos Fotiadis and Tarun Sabharwal and Tim O'Brien and Andy Adam",

year = "2013",

month = jul,

doi = "10.1007/s00330-013-2802-5",

language = "English",

volume = "23",

pages = "1933--1939",

journal = "European Radiology",

issn = "0938-7994",

publisher = "Springer Verlag",

number = "7",

}

TY - JOUR

T1 - Percutaneous radiofrequency ablation of small renal tumours in patients with a single functioning kidney

T2 - long-term results

AU - Krokidis, Miltiadis

AU - Spiliopoulos, Stavros

AU - Jarzabek, Magdalena

AU - Fotiadis, Nikos

AU - Sabharwal, Tarun

AU - O'Brien , Tim

AU - Adam, Andy

PY - 2013/7

Y1 - 2013/7

N2 - Objectives To evaluate the long-term results of percutaneous radiofrequency ablation (RFA) of small renal tumours in patients with a single functioning kidney (SFK). Methods This is a single-centre prospective study. Patients with an SFK and a tumour smaller than 3.5 cm, treated with RFA over a 7.5-year period, were included. Nineteen consecutive patients (12 male), aged between 33 and 83 years (mean 61.4), were treated for 23 lesions. Primary endpoints were technical success and tumour recurrence rate. Secondary endpoints were the deterioration of renal function and overall survival rate. Results The mean follow-up was 56.1 months (range 36-102). Primary technical success was 100 %. There were no major peri-procedural complications. In two cases, minor complications occurred. There was no significant difference between the baseline glomerular filtration rate (GFR) and GFR at 3, 12 and 24 months post-procedure. In four lesions (17 %), recurrence was detected and an additional RFA session was performed. None of the patients developed renal failure during their lifetime. Three of the patients died because of other reasons. Conclusions Percutaneous RFA of small renal tumours in patients with an SFK offers very satisfactory long-term results regarding preservation of renal function, local tumour control and overall survival. Key Points Tumour in a single functioning kidney requires minimally invasive treatment. Radiofrequency ablation plays an established role in managing small renal tumours. Long-term results of radiofrequency ablation have shown satisfactory local tumour control. Long-term results have also shown that renal function may be preserved.

AB - Objectives To evaluate the long-term results of percutaneous radiofrequency ablation (RFA) of small renal tumours in patients with a single functioning kidney (SFK). Methods This is a single-centre prospective study. Patients with an SFK and a tumour smaller than 3.5 cm, treated with RFA over a 7.5-year period, were included. Nineteen consecutive patients (12 male), aged between 33 and 83 years (mean 61.4), were treated for 23 lesions. Primary endpoints were technical success and tumour recurrence rate. Secondary endpoints were the deterioration of renal function and overall survival rate. Results The mean follow-up was 56.1 months (range 36-102). Primary technical success was 100 %. There were no major peri-procedural complications. In two cases, minor complications occurred. There was no significant difference between the baseline glomerular filtration rate (GFR) and GFR at 3, 12 and 24 months post-procedure. In four lesions (17 %), recurrence was detected and an additional RFA session was performed. None of the patients developed renal failure during their lifetime. Three of the patients died because of other reasons. Conclusions Percutaneous RFA of small renal tumours in patients with an SFK offers very satisfactory long-term results regarding preservation of renal function, local tumour control and overall survival. Key Points Tumour in a single functioning kidney requires minimally invasive treatment. Radiofrequency ablation plays an established role in managing small renal tumours. Long-term results of radiofrequency ablation have shown satisfactory local tumour control. Long-term results have also shown that renal function may be preserved.

KW - Renal cancer

KW - Nephrons

KW - Radiofrequency catheter ablation

KW - Ablation techniques

KW - Nephrectomy

KW - SOLITARY KIDNEY

KW - CELL CARCINOMA

KW - ETHANOL INJECTION

KW - OUTCOMES

KW - MASSES

KW - CRYOABLATION

KW - EXPERIENCE

KW - FEATURES

KW - CANCER

KW - VIVO

U2 - 10.1007/s00330-013-2802-5

DO - 10.1007/s00330-013-2802-5

M3 - Article

SN - 0938-7994

VL - 23

SP - 1933

EP - 1939

JO - European Radiology

JF - European Radiology

IS - 7

ER -

Percutaneous radiofrequency ablation of small renal tumours in patients with a single functioning kidney: long-term results

Abstract

Keywords

UN SDGs

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