Phaeochromcytoma crisis

B. C. Whitelaw*, J. K. Prague, O. G. Mustafa, K-M. Schulte, P. A. Hopkins, J. A. Gilbert, A. M. McGregor, S. J. B. Aylwin

*Corresponding author for this work

    Research output: Contribution to journalArticlepeer-review

    84 Citations (Scopus)

    Abstract

    Phaeochromcytoma crisis is an endocrine emergency associated with significant mortality. There is little published guidance on the management of Phaeochromcytoma crisis. This clinical practice update summarizes the relevant published literature, including a detailed review of cases published in the past 5years, and a proposed classification system. We review the recommended management of Phaeochromcytoma crisis including the use of alpha-blockade, which is strongly associated with survival of a crisis. Mechanical circulatory supportive therapy (including intra-aortic balloon pump or extra-corporeal membrane oxygenation) is strongly recommended for patients with sustained hypotension. Surgical intervention should be deferred until medical stabilization is achieved.

    Original languageEnglish
    Pages (from-to)13-22
    Number of pages10
    JournalClinical endocrinology
    Volume80
    Issue number1
    DOIs
    Publication statusPublished - Jan 2014

    Keywords

    • INTERLEUKIN-6 PRODUCING PHEOCHROMOCYTOMA
    • EXTRACORPOREAL MEMBRANE-OXYGENATION
    • CARDIOGENIC-SHOCK
    • HYPERTENSIVE CRISIS
    • SEPTIC SHOCK
    • UNDIAGNOSED PHEOCHROMOCYTOMA
    • PERIOPERATIVE MANAGEMENT
    • CARDIOPULMONARY BYPASS
    • INFLAMMATORY SYNDROME
    • MULTISYSTEM CRISIS

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