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Pharmacogenetic Testing in Psychiatry: A Review of Features and Clinical Realities

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Pharmacogenetic Testing in Psychiatry: A Review of Features and Clinical Realities. / de Leon, Jose; Arranz, Maria J.; Ruano, Gualberto.

In: Clinics in Laboratory Medicine, Vol. 28, No. 4, 12.2008, p. 599 - 617.

Research output: Contribution to journalArticle

Harvard

de Leon, J, Arranz, MJ & Ruano, G 2008, 'Pharmacogenetic Testing in Psychiatry: A Review of Features and Clinical Realities', Clinics in Laboratory Medicine, vol. 28, no. 4, pp. 599 - 617. https://doi.org/10.1016/j.cll.2008.05.003

APA

de Leon, J., Arranz, M. J., & Ruano, G. (2008). Pharmacogenetic Testing in Psychiatry: A Review of Features and Clinical Realities. Clinics in Laboratory Medicine, 28(4), 599 - 617. https://doi.org/10.1016/j.cll.2008.05.003

Vancouver

de Leon J, Arranz MJ, Ruano G. Pharmacogenetic Testing in Psychiatry: A Review of Features and Clinical Realities. Clinics in Laboratory Medicine. 2008 Dec;28(4):599 - 617. https://doi.org/10.1016/j.cll.2008.05.003

Author

de Leon, Jose ; Arranz, Maria J. ; Ruano, Gualberto. / Pharmacogenetic Testing in Psychiatry: A Review of Features and Clinical Realities. In: Clinics in Laboratory Medicine. 2008 ; Vol. 28, No. 4. pp. 599 - 617.

Bibtex Download

@article{20c786e7c8b645da9d02c1c131581991,
title = "Pharmacogenetic Testing in Psychiatry: A Review of Features and Clinical Realities",
abstract = "This article focuses on the first generation of pharmacogenetic tests that are potentially useful in psychiatry All pharmacogenetic tests currently on the market, or soon to be marketed in psychiatry, for which some information has been published in peer-reviewed journal articles (or abstracts), were selected. Five pharmacogenetic tests are reviewed in detail: the Roche AmpliChip CYP450 Test, the Luminex Tag-It Mutation Detection Kit, the LGC clozapine response test, the PGxPredict: Clozapine test, and the Genomas PhyzioType system. After reviewing these tests, three practical aspects of implementing pharmacogenetic testing in psychiatric clinical practice are briefly reviewed: (1) the evaluation of these tests in clinical practice, (2) cost-effectiveness, and (3) regulatory oversight. Finally, the future of these and other pharmacogenetic tests in psychiatry is discussed.",
author = "{de Leon}, Jose and Arranz, {Maria J.} and Gualberto Ruano",
year = "2008",
month = "12",
doi = "10.1016/j.cll.2008.05.003",
language = "English",
volume = "28",
pages = "599 -- 617",
journal = "Clinics in Laboratory Medicine",
issn = "0272-2712",
publisher = "W.B. Saunders Ltd",
number = "4",

}

RIS (suitable for import to EndNote) Download

TY - JOUR

T1 - Pharmacogenetic Testing in Psychiatry: A Review of Features and Clinical Realities

AU - de Leon, Jose

AU - Arranz, Maria J.

AU - Ruano, Gualberto

PY - 2008/12

Y1 - 2008/12

N2 - This article focuses on the first generation of pharmacogenetic tests that are potentially useful in psychiatry All pharmacogenetic tests currently on the market, or soon to be marketed in psychiatry, for which some information has been published in peer-reviewed journal articles (or abstracts), were selected. Five pharmacogenetic tests are reviewed in detail: the Roche AmpliChip CYP450 Test, the Luminex Tag-It Mutation Detection Kit, the LGC clozapine response test, the PGxPredict: Clozapine test, and the Genomas PhyzioType system. After reviewing these tests, three practical aspects of implementing pharmacogenetic testing in psychiatric clinical practice are briefly reviewed: (1) the evaluation of these tests in clinical practice, (2) cost-effectiveness, and (3) regulatory oversight. Finally, the future of these and other pharmacogenetic tests in psychiatry is discussed.

AB - This article focuses on the first generation of pharmacogenetic tests that are potentially useful in psychiatry All pharmacogenetic tests currently on the market, or soon to be marketed in psychiatry, for which some information has been published in peer-reviewed journal articles (or abstracts), were selected. Five pharmacogenetic tests are reviewed in detail: the Roche AmpliChip CYP450 Test, the Luminex Tag-It Mutation Detection Kit, the LGC clozapine response test, the PGxPredict: Clozapine test, and the Genomas PhyzioType system. After reviewing these tests, three practical aspects of implementing pharmacogenetic testing in psychiatric clinical practice are briefly reviewed: (1) the evaluation of these tests in clinical practice, (2) cost-effectiveness, and (3) regulatory oversight. Finally, the future of these and other pharmacogenetic tests in psychiatry is discussed.

U2 - 10.1016/j.cll.2008.05.003

DO - 10.1016/j.cll.2008.05.003

M3 - Article

VL - 28

SP - 599

EP - 617

JO - Clinics in Laboratory Medicine

JF - Clinics in Laboratory Medicine

SN - 0272-2712

IS - 4

ER -

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