Piezo2 channel regulates RhoA and actin cytoskeleton to promote cell mechanobiological responses

Carlos Pardo-Pastor; Fanny Rubio-Moscardo; Marina Vogel-Gonzalez; Selma A. Serra; Alexandros Afthinos; Sanela Mrkonjic; Olivier Destaing; Juan F. Abenza; Jose M. Fernandez-Fernandez; Xavier Trepat; Corinne Albiges-Rizo; Konstantinos Konstantopoulos; Miguel A. Valverde

doi:10.1073/pnas.1718177115

Piezo2 channel regulates RhoA and actin cytoskeleton to promote cell mechanobiological responses

Carlos Pardo-Pastor, Fanny Rubio-Moscardo, Marina Vogel-Gonzalez, Selma A. Serra, Alexandros Afthinos, Sanela Mrkonjic, Olivier Destaing, Juan F. Abenza, Jose M. Fernandez-Fernandez, Xavier Trepat, Corinne Albiges-Rizo, Konstantinos Konstantopoulos, Miguel A. Valverde

Randall Centre of Cell & Molecular Biophysics

Research output: Contribution to journal › Article › peer-review

154 Citations (Scopus)

Original language	English
Pages (from-to)	1925-1930
Journal	Proceedings of the National Academy of Sciences of the United States of America
Volume	115
Issue number	8
DOIs	https://doi.org/10.1073/pnas.1718177115
Publication status	Published - 20 Feb 2018

Keywords

mechanotransduction
calcium signaling
RhoA
actin stress fibers
cancer

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This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1073/pnas.1718177115

Cite this

Pardo-Pastor, C., Rubio-Moscardo, F., Vogel-Gonzalez, M., Serra, S. A., Afthinos, A., Mrkonjic, S., Destaing, O., Abenza, J. F., Fernandez-Fernandez, J. M., Trepat, X., Albiges-Rizo, C., Konstantopoulos, K., & Valverde, M. A. (2018). Piezo2 channel regulates RhoA and actin cytoskeleton to promote cell mechanobiological responses. Proceedings of the National Academy of Sciences of the United States of America, 115(8), 1925-1930. https://doi.org/10.1073/pnas.1718177115

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title = "Piezo2 channel regulates RhoA and actin cytoskeleton to promote cell mechanobiological responses",

keywords = "mechanotransduction, calcium signaling, RhoA, actin stress fibers, cancer",

author = "Carlos Pardo-Pastor and Fanny Rubio-Moscardo and Marina Vogel-Gonzalez and Serra, {Selma A.} and Alexandros Afthinos and Sanela Mrkonjic and Olivier Destaing and Abenza, {Juan F.} and Fernandez-Fernandez, {Jose M.} and Xavier Trepat and Corinne Albiges-Rizo and Konstantinos Konstantopoulos and Valverde, {Miguel A.}",

year = "2018",

month = feb,

day = "20",

doi = "10.1073/pnas.1718177115",

language = "English",

volume = "115",

pages = "1925--1930",

journal = "Proceedings of the National Academy of Sciences of the United States of America",

issn = "0027-8424",

publisher = "National Academy of Sciences",

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Pardo-Pastor, C, Rubio-Moscardo, F, Vogel-Gonzalez, M, Serra, SA, Afthinos, A, Mrkonjic, S, Destaing, O, Abenza, JF, Fernandez-Fernandez, JM, Trepat, X, Albiges-Rizo, C, Konstantopoulos, K & Valverde, MA 2018, 'Piezo2 channel regulates RhoA and actin cytoskeleton to promote cell mechanobiological responses', Proceedings of the National Academy of Sciences of the United States of America, vol. 115, no. 8, pp. 1925-1930. https://doi.org/10.1073/pnas.1718177115

Piezo2 channel regulates RhoA and actin cytoskeleton to promote cell mechanobiological responses. / Pardo-Pastor, Carlos; Rubio-Moscardo, Fanny; Vogel-Gonzalez, Marina et al.
In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 115, No. 8, 20.02.2018, p. 1925-1930.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Piezo2 channel regulates RhoA and actin cytoskeleton to promote cell mechanobiological responses

AU - Pardo-Pastor, Carlos

AU - Rubio-Moscardo, Fanny

AU - Vogel-Gonzalez, Marina

AU - Serra, Selma A.

AU - Afthinos, Alexandros

AU - Mrkonjic, Sanela

AU - Destaing, Olivier

AU - Abenza, Juan F.

AU - Fernandez-Fernandez, Jose M.

AU - Trepat, Xavier

AU - Albiges-Rizo, Corinne

AU - Konstantopoulos, Konstantinos

AU - Valverde, Miguel A.

PY - 2018/2/20

Y1 - 2018/2/20

KW - mechanotransduction

KW - calcium signaling

KW - RhoA

KW - actin stress fibers

KW - cancer

U2 - 10.1073/pnas.1718177115

DO - 10.1073/pnas.1718177115

M3 - Article

SN - 0027-8424

VL - 115

SP - 1925

EP - 1930

JO - Proceedings of the National Academy of Sciences of the United States of America

JF - Proceedings of the National Academy of Sciences of the United States of America

IS - 8

ER -