Pineal function: Impact of microarray analysis

David C. Klein, Michael J. Bailey, David A. Carter, Jong-so Kim, Qiong Shi, Anthony K. Ho, Constance L. Chik, Pascaline Gaildrat, Fabrice Morin, Surajit Ganguly, Martin F. Rath, Morten Moller, David Sugden, Zoila G. Rangel, Peter J. Munson, Joan L. Weller, Steven L. Coon

Research output: Contribution to journalConference paper

43 Citations (Scopus)

Abstract

Microarray analysis has provided a new understanding of pineal function by identifying genes that are highly expressed in this tissue relative to other tissues and also by identifying over 600 genes that are expressed on a 24-h schedule. This effort has highlighted surprising similarity to the retina and has provided reason to explore new avenues of study including intracellular signaling, signal transduction, transcriptional cascades, thyroid/retinoic acid hormone signaling, metal biology, RNA splicing, and the role the pineal gland plays in the immune/inflammation response. The new foundation that microarray analysis has provided will broadly support future research on pineal function. Published by Elsevier Ireland Ltd.
Original languageEnglish
Pages (from-to)170 - 183
Number of pages14
JournalMolecular and Cellular Endocrinology
Volume314
Issue number2
DOIs
Publication statusPublished - 27 Jan 2010
EventSummer Neuropeptide Conference/5th International Symposium on Signal Transduction in Health and Disease (STADY V) - Tel Aviv, Israel
Duration: 22 Oct 200824 Oct 2008

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