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Planning experiments: Updated guidance on experimental design and analysis and their reporting III

Research output: Contribution to journalEditorialpeer-review

Michael J. Curtis, Stephen P.H. Alexander, Giuseppe Cirino, Christopher H. George, David A. Kendall, Paul A. Insel, Angelo A. Izzo, Yong Ji, Reynold A. Panettieri, Hemal H. Patel, Christopher G. Sobey, S. Clare Stanford, Phil Stanley, Barbara Stefanska, Gary J. Stephens, Mauro M. Teixeira, Nathalie Vergnolle, Amrita Ahluwalia

Original languageEnglish
Pages (from-to)3907-3913
Number of pages7
JournalBritish Journal of Pharmacology
Issue number15
Accepted/In press2022
PublishedAug 2022

Bibliographical note

Funding Information: We would like to thank the BJP Editorial Board and the BJP Press Editors: Mick Bakhle, Andy Ramage, Jim Docherty and Brian King, for their valuable contributions. We would also like to thank Anita Bandrowski of Sciscore for providing the Sciscore data shown within the manuscript. Publisher Copyright: © 2022 The British Pharmacological Society.

King's Authors


Scientists who plan to publish in British Journal of Pharmacology (BJP) must read this article before undertaking a study. This editorial provides guidance for the design of experiments. We have published previously two guidance documents on experimental design and analysis (Curtis et al., 2015; Curtis et al., 2018). This update clarifies and simplifies the requirements on design and analysis for BJP manuscripts. This editorial also details updated requirements following an audit and discussion on best practice by the BJP editorial board. Explanations for the requirements are provided in the previous articles. Here, we address new issues that have arisen in the course of handling manuscripts and emphasise three aspects of design that continue to present the greatest challenge to authors: randomisation, blinded analysis and balance of group sizes.

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