Abstract
PURPOSE OF REVIEW: (Poly)phenols are bioactive compounds in plant-based foods with well documented health benefits. Their metabolism in dependent on gut microbiota composition, diversity, and function, which modulate their bioavailability and physiological effects. This review examines recent insights into (poly)phenol-gut microbiota interactions, emphasizing their relevance in mediating health benefits and mechanisms of action.
RECENT FINDINGS: Recent studies have identified a high interindividual variability in (poly)phenol metabolism, explored microbial-derived metabolites with potential health benefits, and revealed bidirectional influences between (poly)phenols and gut microbiota composition. Advances in analytical techniques and large-scale studies have refined our understanding of these interactions, but inconsistencies remain in linking specific microbial signatures to health outcomes.
SUMMARY: Standardized methodologies and long-term studies are needed to clarify the impact of (poly)phenol-derived metabolites on human health. Future research should focus on personalized and targeted nutrition approaches to optimize (poly)phenol benefits.
| Original language | English |
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| Journal | Current Opinion in Clinical Nutrition and Metabolic Care |
| DOIs | |
| Publication status | E-pub ahead of print - 29 Apr 2025 |