Postnatal Growth and Mental Development: Evidence for a “Sensitive Period”

David Skuse*, Andrew Pickles, Dieter Wolke, Sheena Reilly

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

97 Citations (Scopus)

Abstract

Abstract For many years it has been suspected that severely impaired somatic growth during early postnatal life can be associated with the subsequent impairment of mental abilities. This study aimed to test that, hypothesis on the basis of data gathered from a prospective whole population survey of infant development in south London. A year's birth cohort of 1558 full‐term singletons was monitored: 47 otherwise, healthy cases with serious growth faltering in the first year were recruited. Mental and psychomotor abilities were assessed at 15 months. Potentially confounding psychosocial variables, including cognitive stimulation received at home, were measured contemporaneously. A statistical model was constructed that enabled the timing, duration and severity of growth faltering to be used as predictors of mental functioning. Up to 37% of the variance in cognitive and psychomotor outcome at 15 months can be explained by the model. The first few postnatal months appear to constitute a “sensitive period” for the relationship between growth and mental development.

Original languageEnglish
Pages (from-to)521-545
Number of pages25
JournalJournal of child psychology and psychiatry
Volume35
Issue number3
Early online dateMar 1994
DOIs
Publication statusE-pub ahead of print - Mar 1994

Keywords

  • cognition
  • failure to thrive
  • growth
  • infant
  • psychosocial deprivation

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