King's College London

Phase I/II open-label trial of intravenous allogeneic mesenchymal stromal cell therapy in adults with recessive dystrophic epidermolysis bullosa

Rashidghamat, E., Kadiyirire, T., Ayis, S., Petrof, G., Liu, L., Pullabhatla, V., Ainali, C., Guy, A., Aristodemou, S., McMillan, J. R., Ozoemena, L., Mee, J., Pramanik, R., Saxena, A., Nuamah, R., de Rinaldis, E., Serrano, S., Maurin, C., Martinez-Queipo, M., Lwin, S. & 10 others, Ilic, D., Martinez, A. E., Dazzi, F., Slaper-Cortenbach, I., Westinga, K., Zeddies, S., van den Broek, M., Onoufriadis, A., Mellerio, J. & McGrath, J. A., 28 Nov 2019, In: Journal of the American Academy of Dermatology.

Research output: Contribution to journal › Article › peer-review

Generation and Clinical Application of Gene-Modified Autologous Epidermal Sheets in Netherton Syndrome: Lessons Learned from a Phase 1 Trial

Di, W. L., Lwin, S. M., Petrova, A., Bernadis, C., Syed, F., Farzaneh, F., Moulding, D., Martinez, A. E., Sebire, N. J., Rampling, D., Virasami, A., Zamiri, M., Wang, W., Hara, H., Kadiyirire, T., Abdul-Wahab, A., Martinez-Queipo, M., Harper, J. I., McGrath, J. A., Thrasher, A. J. & 2 others, Mellerio, J. E. & Qasim, W., 17 Sep 2019, In: Human Gene Therapy. 30, 9, p. 1067-1078 12 p.

Research output: Contribution to journal › Article › peer-review

Safety and early efficacy outcomes for lentiviral fibroblast gene therapy in recessive dystrophic epidermolysis bullosa

Lwin, S. M., Syed, F., Di, W., Kadiyirire, T., Liu, L., Guy, A., Petrova, A., Abdul-Wahab, A., Reid, F., Phillips, R., Elstad, M., Georgiadis, C., Aristodemou, S., Lovell, P. A., Mcmillan, J. R., Mee, J., Miskinyte, S., Titeux, M., Ozoemena, L., Pramanik, R. & 21 others, Serrano, S., Rowles, R., Maurin, C., Orrin, E., Martinez-Queipo, M., Rashidghamat, E., Tziotzios, C., Onoufriadis, A., Chen, M., Chan, L., Farzaneh, F., Del Rio, M., Tolar, J., Bauer, J. W., Larcher, F., Antoniou, M. N., Hovnanian, A., Thrasher, A. J., Mellerio, J. E., Qasim, W. & Mcgrath, J. A., 6 Jun 2019, In: JCI Insight. 4, 11, :e126243.

Research output: Contribution to journal › Article › peer-review

EBGene trial: patient preselection outcomes for the European GENEGRAFT ex vivo phase I/II gene therapy trial for recessive dystrophic epidermolysis bullosa

Gaucher, S., Lwin, S. M., Titeux, M., Abdul-Wahab, A., Pironon, N., Izmiryan, A., Miskinyte, S., Ganier, C., Duchatelet, S., Mellerio, J. E., Bourrat, E., McGrath, J. A. & Hovnanian, A., 1 Jan 2019, In: British Journal of Dermatology.

Research output: Contribution to journal › Letter › peer-review

227 Patient pre-selection outcomes for the European GENEGRAFT ex vivo phase I/II gene therapy trial for recessive dystrophic epidermolysis bullosa: ESDR 2017 Annual Meeting47th Annual ESDR Meeting

Lwin, S. M., Gaucher, S., Titeux, M., Abdul-Wahab, A., Pironon, N., Miskinyte, S., GANIER, C., Duchatelet, S., McGrath, J. & Hovnanian, A., 8 Sep 2017, In: Journal of Investigative Dermatology. 137, 10, Supplement 2, p. S231

Research output: Contribution to journal › Article › peer-review

Metabolic perturbations in fibrosis disease

Ung, C. Y., Onoufriadis, A., Parsons, M., McGrath, J. & Shaw, T., 25 Aug 2021, (Accepted/In press) In: International Journal of Biochemistry and Cell Biology.

Research output: Contribution to journal › Review article › peer-review

Spatial activation of ezrin by epidermal growth factor receptor and focal adhesion kinase co-ordinates epithelial cell migration

Chan, G. K., McGrath, J. & Parsons, M., 11 Aug 2021, In: Open Biology. 11, 8, p. 210166 1 p., 210166.

Research output: Contribution to journal › Article › peer-review

A multicenter randomized controlled trial indicates that paclitaxel-coated balloons provide no benefit for arteriovenous fistulas

Karunanithy, N., Robinson, E. J., Ahmad, F., Burton, J. O., Calder, F., Coles, S., Das, N., Dorling, A., Forman, C., Jaffer, O., Lawman, S., Lakshminarayan, R., Lewlellyn, R., Peacock, J. L., Ramnarine, R., Mesa, I. R., Shaikh, S., Simpson, J., Steiner, K., Suckling, R. & 8 others, Szabo, L., Turner, D., Wadoodi, A., Wang, Y., Weir, G., Wilkins, C. J., Gardner, L. M. & Robson, M. G., Aug 2021, In: Kidney International. 100, 2, p. 447-456 10 p.

Research output: Contribution to journal › Article › peer-review

Adiponectin is associated with insulin sensitivity in white European men but not black African men

Hakim, O., Bello, O., Ladwa, M., Shojaee-Moradie, F., Jackson, N., Peacock, J. L., Umpleby, A. M., Charles-Edwards, G., Amiel, S. A. & Goff, L. M., Aug 2021, In: Diabetic Medicine. 38, 8, e14571.

Research output: Contribution to journal › Article › peer-review

Synergistic multiple early therapy (SMET) for inflammatory diseases with pathogenic autoinflammatory feedback circuits

McFadden, J. P., Cunningham, L. S., Ferguson, F. J., Tziotzios, C. & McGrath, J. A., Aug 2021, In: British Journal of Dermatology. 185, 2, p. 469-470 2 p.

Research output: Contribution to journal › Letter › peer-review

The Polyamine Regulator AMD1 Upregulates Spermine Levels to Drive Epidermal Differentiation

Rahim, A. B., Lim, H. K., Tan, C. Y. R., Jia, L., Leo, V. I., Uemura, T., Hardman-Smart, J., Common, J. E. A., Lim, T. C., Bellanger, S., Paus, R., Igarashi, K., Yang, H. & Vardy, L. A., Sep 2021, In: Journal of Investigative Dermatology. 141, 9, p. 2178-2188.e6

Research output: Contribution to journal › Article › peer-review

B lymphocytes accumulate and proliferate in human skin at sites of cutaneous antigen challenge

Egbuniwe, I. U., Harris, R. J., Nakamura, M., Nestle, F. O., Akbar, A. N., Karagiannis, S. N. & Lacy, K. E., 26 Aug 2021, In: Journal of Investigative Dermatology.

Research output: Contribution to journal › Article › peer-review

Meeting Report: Psoriasis Stratification to Optimize Relevant Therapy Showcase

PSORT consortium, Aug 2021, In: Journal of Investigative Dermatology. 141, 8, p. 1872-1878 7 p.

Research output: Contribution to journal › Short survey › peer-review

Quantitative Evaluation of Biologic Therapy Options for Psoriasis: A Systematic Review and Network Meta-Analysis–Correction

Smith, C. H., Mahil, S. K., Yiu, Z. Z. N., Bale, T., Burden, A. D., Coates, L. C., McGuire, A., Murphy, R., Owen, C. M., Parslew, R., Uthman, O. A., Woolf, R. T., Manounah, L., Ezejimofor, M. C., Exton, L. S. & Mohd Mustapa, M. F., Jan 2021, In: Journal of Investigative Dermatology. 141, 1, p. 177-181 5 p.

Research output: Contribution to journal › Article › peer-review

Perspective and Consensus Opinion: Good Practices for Using Organotypic Skin and Epidermal Equivalents in Experimental Dermatology Research

2019 Barrier Function of Mammalian Skin Gordon Research Conference, Waterville Valley, New Hampshire, Jan 2021, In: Journal of Investigative Dermatology. 141, 1, p. 203-205 3 p.

Research output: Contribution to journal › Article › peer-review