@inbook{2846214141b04965963b88fcac9e78b1,
title = "Predicting first-episode psychosis associated with cannabis use with artificial neural networks and deep learning",
abstract = "In recent years, a number of researches started to investigate the existence of links between cannabis use and psychotic disorder. More recently, artificial neural networks and in particular deep learning have set a revolutionary wave in pattern recognition and machine learning. This study proposes a novel machine learning approach based on neural network and deep learning algorithms, to developing highly accurate predictive models for the onset of first-episode psychosis. Our approach is based also on a novel methodology of optimising and post-processing the predictive models in a computationally intensive framework. A study of the trade-off between the volume of the data and the extent of uncertainty due to missing values, both of which influencing the predictive performance, enhanced this approach. Furthermore, we extended our approach by proposing and encapsulating a novel post-processing k-fold cross-testing method in order to further optimise, and test these models. The results show that the average accuracy in predicting first-episode psychosis achieved by our models in intensive Monte Carlo simulation, is about 89%.",
keywords = "Cannabis use, Classification, Deep learning, First-episode psychosis, Missing data based uncertainty, Monte Carlo simulation, Neural network, Post-processing, Precision medicine, Prediction modelling",
author = "Daniel Stamate and Wajdi Alghamdi and Daniel Stahl and Ida Pu and Fionn Murtagh and Danielle Belgrave and Robin Murray and {di Forti}, Marta",
note = "final proof of authors; 17th International Conference on Information Processing and Management of Uncertainty in Knowledge-Based Systems, IPMU 2018 ; Conference date: 11-06-2018 Through 15-06-2018",
year = "2018",
month = may,
day = "18",
doi = "10.1007/978-3-319-91479-4_57",
language = "English",
isbn = "9783319914787",
series = "Communications in Computer and Information Science",
publisher = "Springer Verlag",
pages = "691--702",
booktitle = "Information Processing and Management of Uncertainty in Knowledge-Based Systems. Applications - 17th International Conference, IPMU 2018, Proceedings",
address = "Germany",
}