Predictors of patient preference for either whole body magnetic resonance imaging (WB-MRI) or CT/ PET-CT for staging colorectal or lung cancer

Streamline Investigators; Anne Miles; Ruth EC Evans; Steve Halligan; Sandy Beare; John Bridgewater; Vicky Goh; Sam M Janes; Neal Navani; Alfred Oliver; Alison Morton; Steve Morris; Andrea Rockall; Stuart A Taylor

doi:10.1111/1754-9485.13038

Predictors of patient preference for either whole body magnetic resonance imaging (WB-MRI) or CT/ PET-CT for staging colorectal or lung cancer

Streamline Investigators, Anne Miles, Ruth EC Evans, Steve Halligan, Sandy Beare, John Bridgewater, Vicky Goh, Sam M Janes, Neal Navani, Alfred Oliver, Alison Morton, Steve Morris, Andrea Rockall, Stuart A Taylor

Research output: Contribution to journal › Article › peer-review

9 Citations (Scopus)

Abstract

INTRODUCTION: Whole body magnetic resonance imaging (WB-MRI) may be more efficient in staging cancers, but can be harder for patients to tolerate. We examined predictors of patient preference for WB-MRI vs. CT/ PET-CT for staging colorectal or lung cancer.

METHODS: Patients recruited prospectively to two multicentre trials comparing diagnostic accuracy of WB-MRI with standard staging scans were sent two questionnaires: the first, administered at trial registration, captured demographics, educational level and comorbidities; the second, administered after staging completion, measured emotional distress (GHQ-12), positive mood (PANAS), perceived scan burden, patients' beliefs about WB-MRI, and preference for either WB-MRI or CT (colorectal trial), WB-MRI or PET-CT (lung trial). Preference for WB-MRI or CT/ PET-CT was analysed using logistic regression.

RESULTS: Baseline and post-staging questionnaires were completed by 97 and 107 patients, respectively. Overall, 56/107 (52%) preferred WB-MRI over standard scans and were more likely to have no additional comorbidities, higher positive mood, greater awareness of potential benefits of WB-MRI and lower levels of perceived WB-MRI scan burden. In adjusted analyses, only awareness of potential WB-MRI benefits remained a significant predictor (OR: 1.516, 95% CIs 1.006-2.284, P = 0.047). Knowledge that WB-MRI does not use radiation predicted preference (adjusted OR: 3.018, 95% CIs 1.099-8.288, P = 0.032), although only 45/107 (42%) patients were aware of this attribute.

CONCLUSIONS: A small majority of patients undergoing staging of colorectal or lung cancer prefer WB-MRI to CT/ PET-CT. Raising awareness of the potential benefits of WB-MRI, notably lack of ionizing radiation, could influence preference.

Original language	English
Pages (from-to)	537-545
Number of pages	9
Journal	Journal of medical imaging and radiation oncology
Volume	64
Issue number	4
Early online date	14 May 2020
DOIs	https://doi.org/10.1111/1754-9485.13038
Publication status	Published - 1 Aug 2020

Keywords

X-ray computed
cancer
magnetic resonance imaging
patient preference
positron emission tomography
tomography

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1111/1754-9485.13038

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Streamline Investigators, Miles, A., Evans, R. EC., Halligan, S., Beare, S., Bridgewater, J., Goh, V., Janes, S. M., Navani, N., Oliver, A., Morton, A., Morris, S., Rockall, A., & Taylor, S. A. (2020). Predictors of patient preference for either whole body magnetic resonance imaging (WB-MRI) or CT/ PET-CT for staging colorectal or lung cancer. Journal of medical imaging and radiation oncology, 64(4), 537-545. https://doi.org/10.1111/1754-9485.13038

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title = "Predictors of patient preference for either whole body magnetic resonance imaging (WB-MRI) or CT/ PET-CT for staging colorectal or lung cancer",

abstract = "INTRODUCTION: Whole body magnetic resonance imaging (WB-MRI) may be more efficient in staging cancers, but can be harder for patients to tolerate. We examined predictors of patient preference for WB-MRI vs. CT/ PET-CT for staging colorectal or lung cancer.METHODS: Patients recruited prospectively to two multicentre trials comparing diagnostic accuracy of WB-MRI with standard staging scans were sent two questionnaires: the first, administered at trial registration, captured demographics, educational level and comorbidities; the second, administered after staging completion, measured emotional distress (GHQ-12), positive mood (PANAS), perceived scan burden, patients' beliefs about WB-MRI, and preference for either WB-MRI or CT (colorectal trial), WB-MRI or PET-CT (lung trial). Preference for WB-MRI or CT/ PET-CT was analysed using logistic regression.RESULTS: Baseline and post-staging questionnaires were completed by 97 and 107 patients, respectively. Overall, 56/107 (52%) preferred WB-MRI over standard scans and were more likely to have no additional comorbidities, higher positive mood, greater awareness of potential benefits of WB-MRI and lower levels of perceived WB-MRI scan burden. In adjusted analyses, only awareness of potential WB-MRI benefits remained a significant predictor (OR: 1.516, 95% CIs 1.006-2.284, P = 0.047). Knowledge that WB-MRI does not use radiation predicted preference (adjusted OR: 3.018, 95% CIs 1.099-8.288, P = 0.032), although only 45/107 (42%) patients were aware of this attribute.CONCLUSIONS: A small majority of patients undergoing staging of colorectal or lung cancer prefer WB-MRI to CT/ PET-CT. Raising awareness of the potential benefits of WB-MRI, notably lack of ionizing radiation, could influence preference.",

keywords = "X-ray computed, cancer, magnetic resonance imaging, patient preference, positron emission tomography, tomography",

author = "{Streamline Investigators} and Anne Miles and Evans, {Ruth EC} and Steve Halligan and Sandy Beare and John Bridgewater and Vicky Goh and Janes, {Sam M} and Neal Navani and Alfred Oliver and Alison Morton and Steve Morris and Andrea Rockall and Taylor, {Stuart A}",

note = "{\textcopyright} 2020 The Authors. Journal of Medical Imaging and Radiation Oncology published by John Wiley & Sons Australia, Ltd on behalf of Royal Australian and New Zealand College of Radiologists.",

year = "2020",

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doi = "10.1111/1754-9485.13038",

language = "English",

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Streamline Investigators, Miles, A, Evans, REC, Halligan, S, Beare, S, Bridgewater, J, Goh, V, Janes, SM, Navani, N, Oliver, A, Morton, A, Morris, S, Rockall, A & Taylor, SA 2020, 'Predictors of patient preference for either whole body magnetic resonance imaging (WB-MRI) or CT/ PET-CT for staging colorectal or lung cancer', Journal of medical imaging and radiation oncology, vol. 64, no. 4, pp. 537-545. https://doi.org/10.1111/1754-9485.13038

TY - JOUR

T1 - Predictors of patient preference for either whole body magnetic resonance imaging (WB-MRI) or CT/ PET-CT for staging colorectal or lung cancer

AU - Streamline Investigators

AU - Miles, Anne

AU - Evans, Ruth EC

AU - Halligan, Steve

AU - Beare, Sandy

AU - Bridgewater, John

AU - Goh, Vicky

AU - Janes, Sam M

AU - Navani, Neal

AU - Oliver, Alfred

AU - Morton, Alison

AU - Morris, Steve

AU - Rockall, Andrea

AU - Taylor, Stuart A

PY - 2020/8/1

Y1 - 2020/8/1

N2 - INTRODUCTION: Whole body magnetic resonance imaging (WB-MRI) may be more efficient in staging cancers, but can be harder for patients to tolerate. We examined predictors of patient preference for WB-MRI vs. CT/ PET-CT for staging colorectal or lung cancer.METHODS: Patients recruited prospectively to two multicentre trials comparing diagnostic accuracy of WB-MRI with standard staging scans were sent two questionnaires: the first, administered at trial registration, captured demographics, educational level and comorbidities; the second, administered after staging completion, measured emotional distress (GHQ-12), positive mood (PANAS), perceived scan burden, patients' beliefs about WB-MRI, and preference for either WB-MRI or CT (colorectal trial), WB-MRI or PET-CT (lung trial). Preference for WB-MRI or CT/ PET-CT was analysed using logistic regression.RESULTS: Baseline and post-staging questionnaires were completed by 97 and 107 patients, respectively. Overall, 56/107 (52%) preferred WB-MRI over standard scans and were more likely to have no additional comorbidities, higher positive mood, greater awareness of potential benefits of WB-MRI and lower levels of perceived WB-MRI scan burden. In adjusted analyses, only awareness of potential WB-MRI benefits remained a significant predictor (OR: 1.516, 95% CIs 1.006-2.284, P = 0.047). Knowledge that WB-MRI does not use radiation predicted preference (adjusted OR: 3.018, 95% CIs 1.099-8.288, P = 0.032), although only 45/107 (42%) patients were aware of this attribute.CONCLUSIONS: A small majority of patients undergoing staging of colorectal or lung cancer prefer WB-MRI to CT/ PET-CT. Raising awareness of the potential benefits of WB-MRI, notably lack of ionizing radiation, could influence preference.

AB - INTRODUCTION: Whole body magnetic resonance imaging (WB-MRI) may be more efficient in staging cancers, but can be harder for patients to tolerate. We examined predictors of patient preference for WB-MRI vs. CT/ PET-CT for staging colorectal or lung cancer.METHODS: Patients recruited prospectively to two multicentre trials comparing diagnostic accuracy of WB-MRI with standard staging scans were sent two questionnaires: the first, administered at trial registration, captured demographics, educational level and comorbidities; the second, administered after staging completion, measured emotional distress (GHQ-12), positive mood (PANAS), perceived scan burden, patients' beliefs about WB-MRI, and preference for either WB-MRI or CT (colorectal trial), WB-MRI or PET-CT (lung trial). Preference for WB-MRI or CT/ PET-CT was analysed using logistic regression.RESULTS: Baseline and post-staging questionnaires were completed by 97 and 107 patients, respectively. Overall, 56/107 (52%) preferred WB-MRI over standard scans and were more likely to have no additional comorbidities, higher positive mood, greater awareness of potential benefits of WB-MRI and lower levels of perceived WB-MRI scan burden. In adjusted analyses, only awareness of potential WB-MRI benefits remained a significant predictor (OR: 1.516, 95% CIs 1.006-2.284, P = 0.047). Knowledge that WB-MRI does not use radiation predicted preference (adjusted OR: 3.018, 95% CIs 1.099-8.288, P = 0.032), although only 45/107 (42%) patients were aware of this attribute.CONCLUSIONS: A small majority of patients undergoing staging of colorectal or lung cancer prefer WB-MRI to CT/ PET-CT. Raising awareness of the potential benefits of WB-MRI, notably lack of ionizing radiation, could influence preference.

KW - X-ray computed

KW - cancer

KW - magnetic resonance imaging

KW - patient preference

KW - positron emission tomography

KW - tomography

UR - http://www.scopus.com/inward/record.url?scp=85084582093&partnerID=8YFLogxK

U2 - 10.1111/1754-9485.13038

DO - 10.1111/1754-9485.13038

M3 - Article

C2 - 32410378

SN - 1754-9477

VL - 64

SP - 537

EP - 545

JO - Journal of medical imaging and radiation oncology

JF - Journal of medical imaging and radiation oncology

IS - 4

ER -

Predictors of patient preference for either whole body magnetic resonance imaging (WB-MRI) or CT/ PET-CT for staging colorectal or lung cancer

Abstract

Keywords

UN SDGs

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