Pregnancy and CKD: Advances in Care and the Legacy of Dr Susan Hou

TY - JOUR

T1 - Pregnancy and CKD

T2 - Advances in Care and the Legacy of Dr Susan Hou

AU - Oliverio, Andrea L.

AU - Bramham, Kate

AU - Hladunewich, Michelle A.

N1 - Funding Information: Dr Oliverio was supported by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) grant K23 DK123413-01. Funding Information: Andrea L. Oliverio, MD, MSc, Kate Bramham, MBBS, PhD, and Michelle A. Hladunewich, MD, MSc. Dr Oliverio was supported by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) grant K23 DK123413-01. Dr Hladunewich declares a grant from Roche Pharmaceuticals to study preeclampsia biomarkers in pregnant women with CKD. The remaining authors declare that they have no relevant financial interests. Received March 21, 2021, in response to an invitation from the journal. Evaluated by 2 external peer reviewers and a member of the Feature Advisory Board, with direct editorial input from the Feature Editor and a Deputy Editor. Accepted in revised form July 13, 2021. Publisher Copyright: © 2021 National Kidney Foundation, Inc.

PY - 2021/12

Y1 - 2021/12

N2 - Dr Susan Hou began her illustrious nephrology career at a time when pregnancy in women with chronic kidney disease (CKD) was hazardous and actively discouraged. Her pioneering research in women's health provided much of the early outcome data that shaped our current understanding of CKD and pregnancy. Although many uncertainties regarding optimal management of this vulnerable patient group remain, recent decades have witnessed important advances and renewed interest in improving care for pregnant women with CKD. Many nephrologists have been inspired by Dr Hou's lifetime of work and are grateful for her generous collaborations. In this In Practice Review, we honor her legacy by providing an update of current literature and clinical management guidance in the context of a clinical case vignette that challenges us to consider the many complex aspects to the counseling and care of women with CKD who desire a pregnancy.

AB - Dr Susan Hou began her illustrious nephrology career at a time when pregnancy in women with chronic kidney disease (CKD) was hazardous and actively discouraged. Her pioneering research in women's health provided much of the early outcome data that shaped our current understanding of CKD and pregnancy. Although many uncertainties regarding optimal management of this vulnerable patient group remain, recent decades have witnessed important advances and renewed interest in improving care for pregnant women with CKD. Many nephrologists have been inspired by Dr Hou's lifetime of work and are grateful for her generous collaborations. In this In Practice Review, we honor her legacy by providing an update of current literature and clinical management guidance in the context of a clinical case vignette that challenges us to consider the many complex aspects to the counseling and care of women with CKD who desire a pregnancy.

KW - Chronic kidney disease (CKD)

KW - family planning

KW - fertility

KW - fetal outcomes

KW - kidney failure

KW - obstetrics

KW - preconception counseling

KW - pregnancy

KW - reproductive health

KW - review

KW - sexual dysfunction

UR - http://www.scopus.com/inward/record.url?scp=85117196217&partnerID=8YFLogxK

U2 - 10.1053/j.ajkd.2021.07.016

DO - 10.1053/j.ajkd.2021.07.016

M3 - Article

AN - SCOPUS:85117196217

SN - 0272-6386

VL - 78

SP - 865

EP - 875

JO - American Journal of Kidney Diseases

JF - American Journal of Kidney Diseases

IS - 6

ER -