Pregnancy in HIV-infected teenagers in London

A. Elgalib; A. Hegazi; A. Samarawickrama; S. Roedling; S. Tariq; E. Draeger; J. Hemelaar; T. Rathnayaka; A. Azwa; D. Hawkins; S. Edwards; K. Perez; J. Russell; C. Wood; M. Poulton; R. Shah; H. Noble; M. Rodgers; G. P. Taylor; J. Anderson; A. de Ruiter

doi:10.1111/j.1468-1293.2010.00878.x

Pregnancy in HIV-infected teenagers in London

A. Elgalib^*, A. Hegazi, A. Samarawickrama, S. Roedling, S. Tariq, E. Draeger, J. Hemelaar, T. Rathnayaka, A. Azwa, D. Hawkins, S. Edwards, K. Perez, J. Russell, C. Wood, M. Poulton, R. Shah, H. Noble, M. Rodgers, G. P. Taylor, J. AndersonA. de Ruiter

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

19 Citations (Scopus)

Abstract

Objective

The aim of the study was to describe pregnancies in HIV-infected teenagers.

Methods

A review of the case notes of HIV-infected pregnant teenagers aged 13-19 years from 12 London hospitals was carried out for the period 2000-2007.

Results

There were 67 pregnancies in 58 young women, of whom one was known to have acquired HIV vertically. The overall mother-to-child transmission (MTCT) rate of HIV was 1.5% (one of 66). There were 66 live births. Median ages at HIV diagnosis and conception were 17 and 18 years, respectively. Sixty-three per cent of women were diagnosed with HIV infection through routine antenatal screening. Eighty-two per cent of pregnancies (41 of 50) were unplanned, with 65% of women (26 of 40) using no contraception. Forty-three per cent of the women (20 of 46) had a past history of a sexually transmitted infection (STI). In 63 pregnancies, antiretroviral therapy was started post-conception, with prevention of HIV MTCT the only indication in 81% of cases. Fifty-eight per cent of those on highly active antiretroviral therapy (HAART) had an undetectable HIV viral load by delivery. Eighty-seven per cent were uncomplicated pregnancies. Seventy-one per cent delivered by Caesarean section and 21% (14 of 64) had a preterm delivery (

Conclusion

Obstetric and virological outcomes were favourable in this group of HIV-infected young women. However, the majority of pregnancies were unplanned with poor documentation of contraception use and advice and low rates of STI screening. A quarter of women conceived again within 12 months of delivery. Effective measures to reduce STIs, unplanned pregnancies and onward HIV transmission in HIV-infected teenagers are needed.

Original language	English
Pages (from-to)	118-123
Number of pages	6
Journal	HIV MEDICINE
Volume	12
Issue number	2
DOIs	https://doi.org/10.1111/j.1468-1293.2010.00878.x
Publication status	Published - Feb 2011

Keywords

HIV infection
pregnancy
teenagers
HUMAN-IMMUNODEFICIENCY-VIRUS
ADOLESCENT GIRLS
UNITED-KINGDOM
RISK-FACTORS
YOUNG
MANAGEMENT
SERVICES
IRELAND
PEOPLE
WOMEN

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1111/j.1468-1293.2010.00878.x

Cite this

Elgalib, A., Hegazi, A., Samarawickrama, A., Roedling, S., Tariq, S., Draeger, E., Hemelaar, J., Rathnayaka, T., Azwa, A., Hawkins, D., Edwards, S., Perez, K., Russell, J., Wood, C., Poulton, M., Shah, R., Noble, H., Rodgers, M., Taylor, G. P., ... de Ruiter, A. (2011). Pregnancy in HIV-infected teenagers in London. HIV MEDICINE, 12(2), 118-123. https://doi.org/10.1111/j.1468-1293.2010.00878.x

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title = "Pregnancy in HIV-infected teenagers in London",

abstract = "ObjectiveThe aim of the study was to describe pregnancies in HIV-infected teenagers.MethodsA review of the case notes of HIV-infected pregnant teenagers aged 13-19 years from 12 London hospitals was carried out for the period 2000-2007.ResultsThere were 67 pregnancies in 58 young women, of whom one was known to have acquired HIV vertically. The overall mother-to-child transmission (MTCT) rate of HIV was 1.5% (one of 66). There were 66 live births. Median ages at HIV diagnosis and conception were 17 and 18 years, respectively. Sixty-three per cent of women were diagnosed with HIV infection through routine antenatal screening. Eighty-two per cent of pregnancies (41 of 50) were unplanned, with 65% of women (26 of 40) using no contraception. Forty-three per cent of the women (20 of 46) had a past history of a sexually transmitted infection (STI). In 63 pregnancies, antiretroviral therapy was started post-conception, with prevention of HIV MTCT the only indication in 81% of cases. Fifty-eight per cent of those on highly active antiretroviral therapy (HAART) had an undetectable HIV viral load by delivery. Eighty-seven per cent were uncomplicated pregnancies. Seventy-one per cent delivered by Caesarean section and 21% (14 of 64) had a preterm delivery (ConclusionObstetric and virological outcomes were favourable in this group of HIV-infected young women. However, the majority of pregnancies were unplanned with poor documentation of contraception use and advice and low rates of STI screening. A quarter of women conceived again within 12 months of delivery. Effective measures to reduce STIs, unplanned pregnancies and onward HIV transmission in HIV-infected teenagers are needed.",

keywords = "HIV infection, pregnancy, teenagers, HUMAN-IMMUNODEFICIENCY-VIRUS, ADOLESCENT GIRLS, UNITED-KINGDOM, RISK-FACTORS, YOUNG, MANAGEMENT, SERVICES, IRELAND, PEOPLE, WOMEN",

author = "A. Elgalib and A. Hegazi and A. Samarawickrama and S. Roedling and S. Tariq and E. Draeger and J. Hemelaar and T. Rathnayaka and A. Azwa and D. Hawkins and S. Edwards and K. Perez and J. Russell and C. Wood and M. Poulton and R. Shah and H. Noble and M. Rodgers and Taylor, {G. P.} and J. Anderson and {de Ruiter}, A.",

year = "2011",

month = feb,

doi = "10.1111/j.1468-1293.2010.00878.x",

language = "English",

volume = "12",

pages = "118--123",

journal = "HIV MEDICINE",

issn = "1464-2662",

publisher = "Wiley-Blackwell",

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Elgalib, A, Hegazi, A, Samarawickrama, A, Roedling, S, Tariq, S, Draeger, E, Hemelaar, J, Rathnayaka, T, Azwa, A, Hawkins, D, Edwards, S, Perez, K, Russell, J, Wood, C, Poulton, M, Shah, R, Noble, H, Rodgers, M, Taylor, GP, Anderson, J & de Ruiter, A 2011, 'Pregnancy in HIV-infected teenagers in London', HIV MEDICINE, vol. 12, no. 2, pp. 118-123. https://doi.org/10.1111/j.1468-1293.2010.00878.x

TY - JOUR

T1 - Pregnancy in HIV-infected teenagers in London

AU - Elgalib, A.

AU - Hegazi, A.

AU - Samarawickrama, A.

AU - Roedling, S.

AU - Tariq, S.

AU - Draeger, E.

AU - Hemelaar, J.

AU - Rathnayaka, T.

AU - Azwa, A.

AU - Hawkins, D.

AU - Edwards, S.

AU - Perez, K.

AU - Russell, J.

AU - Wood, C.

AU - Poulton, M.

AU - Shah, R.

AU - Noble, H.

AU - Rodgers, M.

AU - Taylor, G. P.

AU - Anderson, J.

AU - de Ruiter, A.

PY - 2011/2

Y1 - 2011/2

N2 - ObjectiveThe aim of the study was to describe pregnancies in HIV-infected teenagers.MethodsA review of the case notes of HIV-infected pregnant teenagers aged 13-19 years from 12 London hospitals was carried out for the period 2000-2007.ResultsThere were 67 pregnancies in 58 young women, of whom one was known to have acquired HIV vertically. The overall mother-to-child transmission (MTCT) rate of HIV was 1.5% (one of 66). There were 66 live births. Median ages at HIV diagnosis and conception were 17 and 18 years, respectively. Sixty-three per cent of women were diagnosed with HIV infection through routine antenatal screening. Eighty-two per cent of pregnancies (41 of 50) were unplanned, with 65% of women (26 of 40) using no contraception. Forty-three per cent of the women (20 of 46) had a past history of a sexually transmitted infection (STI). In 63 pregnancies, antiretroviral therapy was started post-conception, with prevention of HIV MTCT the only indication in 81% of cases. Fifty-eight per cent of those on highly active antiretroviral therapy (HAART) had an undetectable HIV viral load by delivery. Eighty-seven per cent were uncomplicated pregnancies. Seventy-one per cent delivered by Caesarean section and 21% (14 of 64) had a preterm delivery (ConclusionObstetric and virological outcomes were favourable in this group of HIV-infected young women. However, the majority of pregnancies were unplanned with poor documentation of contraception use and advice and low rates of STI screening. A quarter of women conceived again within 12 months of delivery. Effective measures to reduce STIs, unplanned pregnancies and onward HIV transmission in HIV-infected teenagers are needed.

AB - ObjectiveThe aim of the study was to describe pregnancies in HIV-infected teenagers.MethodsA review of the case notes of HIV-infected pregnant teenagers aged 13-19 years from 12 London hospitals was carried out for the period 2000-2007.ResultsThere were 67 pregnancies in 58 young women, of whom one was known to have acquired HIV vertically. The overall mother-to-child transmission (MTCT) rate of HIV was 1.5% (one of 66). There were 66 live births. Median ages at HIV diagnosis and conception were 17 and 18 years, respectively. Sixty-three per cent of women were diagnosed with HIV infection through routine antenatal screening. Eighty-two per cent of pregnancies (41 of 50) were unplanned, with 65% of women (26 of 40) using no contraception. Forty-three per cent of the women (20 of 46) had a past history of a sexually transmitted infection (STI). In 63 pregnancies, antiretroviral therapy was started post-conception, with prevention of HIV MTCT the only indication in 81% of cases. Fifty-eight per cent of those on highly active antiretroviral therapy (HAART) had an undetectable HIV viral load by delivery. Eighty-seven per cent were uncomplicated pregnancies. Seventy-one per cent delivered by Caesarean section and 21% (14 of 64) had a preterm delivery (ConclusionObstetric and virological outcomes were favourable in this group of HIV-infected young women. However, the majority of pregnancies were unplanned with poor documentation of contraception use and advice and low rates of STI screening. A quarter of women conceived again within 12 months of delivery. Effective measures to reduce STIs, unplanned pregnancies and onward HIV transmission in HIV-infected teenagers are needed.

KW - HIV infection

KW - pregnancy

KW - teenagers

KW - HUMAN-IMMUNODEFICIENCY-VIRUS

KW - ADOLESCENT GIRLS

KW - UNITED-KINGDOM

KW - RISK-FACTORS

KW - YOUNG

KW - MANAGEMENT

KW - SERVICES

KW - IRELAND

KW - PEOPLE

KW - WOMEN

U2 - 10.1111/j.1468-1293.2010.00878.x

DO - 10.1111/j.1468-1293.2010.00878.x

M3 - Article

SN - 1464-2662

VL - 12

SP - 118

EP - 123

JO - HIV MEDICINE

JF - HIV MEDICINE

IS - 2

ER -

Pregnancy in HIV-infected teenagers in London

Abstract

Keywords

UN SDGs

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