Prenatal diagnosis, prediction of outcome and in utero therapy of isolated congenital diaphragmatic hernia

E Done; L Gucciardo; T Van Mieghem; J Jani; M Cannie; D Van Schoubroeck; R Devlieger; L De Catte; P Klaritsch; S Mayer; V Beck; A Debeer; E Gratacos; K Nicolaides; J Deprest

doi:10.1002/pd.2033

Prenatal diagnosis, prediction of outcome and in utero therapy of isolated congenital diaphragmatic hernia

E Done, L Gucciardo, T Van Mieghem, J Jani, M Cannie, D Van Schoubroeck, R Devlieger, L De Catte, P Klaritsch, S Mayer, V Beck, A Debeer, E Gratacos, K Nicolaides, J Deprest

Research output: Contribution to journal › Literature review › peer-review

80 Citations (Scopus)

Abstract

Congenital diaphragmatic hernia (CDH) can be associated with Genetic or structural anomalies with poor prognosis. In isolated cases, survival is dependent on the degree of lung hypoplasia and liver position. Cases Should be referred in utero to tertiary care centers familiar with this condition both for prediction of outcome as well as timed delivery. The best validated prognostic indicator is the lung area to head Circumference ratio. Ultrasound is used to measure the lung area of the index case, which is then expressed as a proportion of what is expected normally (observed/expected LHR). When O/E LHR is

Original language	English
Pages (from-to)	581 - 591
Number of pages	11
Journal	Prenatal Diagnosis
Volume	28
Issue number	7
DOIs	https://doi.org/10.1002/pd.2033
Publication status	Published - Jul 2008

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Done, E., Gucciardo, L., Van Mieghem, T., Jani, J., Cannie, M., Van Schoubroeck, D., Devlieger, R., De Catte, L., Klaritsch, P., Mayer, S., Beck, V., Debeer, A., Gratacos, E., Nicolaides, K., & Deprest, J. (2008). Prenatal diagnosis, prediction of outcome and in utero therapy of isolated congenital diaphragmatic hernia. Prenatal Diagnosis, 28(7), 581 - 591. https://doi.org/10.1002/pd.2033

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title = "Prenatal diagnosis, prediction of outcome and in utero therapy of isolated congenital diaphragmatic hernia",

abstract = "Congenital diaphragmatic hernia (CDH) can be associated with Genetic or structural anomalies with poor prognosis. In isolated cases, survival is dependent on the degree of lung hypoplasia and liver position. Cases Should be referred in utero to tertiary care centers familiar with this condition both for prediction of outcome as well as timed delivery. The best validated prognostic indicator is the lung area to head Circumference ratio. Ultrasound is used to measure the lung area of the index case, which is then expressed as a proportion of what is expected normally (observed/expected LHR). When O/E LHR is ",

author = "E Done and L Gucciardo and {Van Mieghem}, T and J Jani and M Cannie and {Van Schoubroeck}, D and R Devlieger and {De Catte}, L and P Klaritsch and S Mayer and V Beck and A Debeer and E Gratacos and K Nicolaides and J Deprest",

year = "2008",

month = jul,

doi = "10.1002/pd.2033",

language = "English",

volume = "28",

pages = "581 -- 591",

journal = "Prenatal Diagnosis",

publisher = "John Wiley and Sons Ltd",

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Done, E, Gucciardo, L, Van Mieghem, T, Jani, J, Cannie, M, Van Schoubroeck, D, Devlieger, R, De Catte, L, Klaritsch, P, Mayer, S, Beck, V, Debeer, A, Gratacos, E, Nicolaides, K & Deprest, J 2008, 'Prenatal diagnosis, prediction of outcome and in utero therapy of isolated congenital diaphragmatic hernia', Prenatal Diagnosis, vol. 28, no. 7, pp. 581 - 591. https://doi.org/10.1002/pd.2033

TY - JOUR

T1 - Prenatal diagnosis, prediction of outcome and in utero therapy of isolated congenital diaphragmatic hernia

AU - Done, E

AU - Gucciardo, L

AU - Van Mieghem, T

AU - Jani, J

AU - Cannie, M

AU - Van Schoubroeck, D

AU - Devlieger, R

AU - De Catte, L

AU - Klaritsch, P

AU - Mayer, S

AU - Beck, V

AU - Debeer, A

AU - Gratacos, E

AU - Nicolaides, K

AU - Deprest, J

PY - 2008/7

Y1 - 2008/7

N2 - Congenital diaphragmatic hernia (CDH) can be associated with Genetic or structural anomalies with poor prognosis. In isolated cases, survival is dependent on the degree of lung hypoplasia and liver position. Cases Should be referred in utero to tertiary care centers familiar with this condition both for prediction of outcome as well as timed delivery. The best validated prognostic indicator is the lung area to head Circumference ratio. Ultrasound is used to measure the lung area of the index case, which is then expressed as a proportion of what is expected normally (observed/expected LHR). When O/E LHR is

AB - Congenital diaphragmatic hernia (CDH) can be associated with Genetic or structural anomalies with poor prognosis. In isolated cases, survival is dependent on the degree of lung hypoplasia and liver position. Cases Should be referred in utero to tertiary care centers familiar with this condition both for prediction of outcome as well as timed delivery. The best validated prognostic indicator is the lung area to head Circumference ratio. Ultrasound is used to measure the lung area of the index case, which is then expressed as a proportion of what is expected normally (observed/expected LHR). When O/E LHR is

U2 - 10.1002/pd.2033

DO - 10.1002/pd.2033

M3 - Literature review

VL - 28

SP - 581

EP - 591

JO - Prenatal Diagnosis

JF - Prenatal Diagnosis

IS - 7

ER -

Prenatal diagnosis, prediction of outcome and in utero therapy of isolated congenital diaphragmatic hernia

Abstract

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