Abstract
Hydrophilic interaction chromatography (HILIC) has experienced increasing attention in recent years. Much research has been carried out in the area of HILIC separation mechanisms, column techniques and applications. Because of their good permeability, low resistance to mass transfer and easy preparation within capillaries, hydrophilic monolithic columns represent a trend among novel HILIC column techniques. This review attempts to present an overview of the preparation and applications of HILIC monolithic columns carried out in the past decade. The separation mechanism of various hydrophilic monolithic stationary phases is also reviewed. (C) 2011 Elsevier B.V. All rights reserved.
| Original language | English |
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| Pages (from-to) | 2350 - 2361 |
| Number of pages | 12 |
| Journal | Journal of Chromatography A |
| Volume | 1218 |
| Issue number | 17 |
| DOIs | |
| Publication status | Published - 29 Apr 2011 |
| Event | 4th Summer School of Monolith Technology for Biochromatography, Bioconversion and Phase State Synthesis - Portoroz, Slovenia Duration: 30 May 2010 → 2 Jun 2010 |