Prevalence and clinical severity of mood disorders among first-, second- and third-generation migrants

Baptiste Pignon; Pierre Alexis Geoffroy; Pierre Thomas; Jean Luc Roelandt; Benjamin Rolland; Craig Morgan; Guillaume Vaiva; Ali Amad

doi:10.1016/j.jad.2016.12.039

Prevalence and clinical severity of mood disorders among first-, second- and third-generation migrants

Baptiste Pignon^*, Pierre Alexis Geoffroy, Pierre Thomas, Jean Luc Roelandt, Benjamin Rolland, Craig Morgan, Guillaume Vaiva, Ali Amad

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

33 Citations (Scopus)

Abstract

Background The role of migration as a risk factor remains unknown for mood disorders because of poor data. We sought to examine the prevalence and severity of mood disorders (bipolar disorder (BD), unipolar depressive disorder (UDD) and dysthymia) in first, second, and third generation migrants in France. Methods The Mental Health in the General Population survey interviewed 38,694 individuals. The prevalence of lifetime mood disorders, comorbidities, and clinical features was compared between migrants and non-migrants and by generation. All analyses were adjusted for age, sex and level of education. Results The prevalence of any lifetime mood disorder was higher in migrants compared with non-migrants (OR=1.36, 95% CI [1.27–1.45]). This increased prevalence was significant for UDD (OR=1.44, 95% CI [1.34–1.54]), but not for BD (OR=1.15, 95% CI [0.96–1.36]) or dysthymia (OR=1.09, 95% CI [0.94–1.27]), although the prevalence of BD was increased in the third generation (OR=1.27, 95% CI [1.01–1.60]). Migrants with BD or UDD were more likely to display a comorbid psychotic disorder compared to non-migrants with BD or UDD. Cannabis-use disorders were more common in migrant groups for the 3 mood disorders, whereas alcohol-use disorders were higher in migrants with UDD. Posttraumatic stress disorder was more frequent among migrants with UDD. Limitations The study used cross-sectional prevalence data and could be biased by differences in the course of disease according to migrant status. Moreover, this design does not allow causality conclusion or generalization of the main findings. Conclusion Mood disorders are more common among migrants, especially UDD. Moreover, migrants with mood disorders presented with a more severe profile, with increased rates of psychotic and substance-use disorders.

Original language	English
Pages (from-to)	174-180
Number of pages	7
Journal	Journal of Affective Disorders
Volume	210
DOIs	https://doi.org/10.1016/j.jad.2016.12.039
Publication status	Published - 1 Mar 2017

Keywords

Bipolar disorder
Comorbidities
Depressive disorder
Dysthymia
Migration

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.jad.2016.12.039

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@article{4c55fc279f9f463aa8ead191a8f74849,

title = "Prevalence and clinical severity of mood disorders among first-, second- and third-generation migrants",

abstract = "Background The role of migration as a risk factor remains unknown for mood disorders because of poor data. We sought to examine the prevalence and severity of mood disorders (bipolar disorder (BD), unipolar depressive disorder (UDD) and dysthymia) in first, second, and third generation migrants in France. Methods The Mental Health in the General Population survey interviewed 38,694 individuals. The prevalence of lifetime mood disorders, comorbidities, and clinical features was compared between migrants and non-migrants and by generation. All analyses were adjusted for age, sex and level of education. Results The prevalence of any lifetime mood disorder was higher in migrants compared with non-migrants (OR=1.36, 95% CI [1.27–1.45]). This increased prevalence was significant for UDD (OR=1.44, 95% CI [1.34–1.54]), but not for BD (OR=1.15, 95% CI [0.96–1.36]) or dysthymia (OR=1.09, 95% CI [0.94–1.27]), although the prevalence of BD was increased in the third generation (OR=1.27, 95% CI [1.01–1.60]). Migrants with BD or UDD were more likely to display a comorbid psychotic disorder compared to non-migrants with BD or UDD. Cannabis-use disorders were more common in migrant groups for the 3 mood disorders, whereas alcohol-use disorders were higher in migrants with UDD. Posttraumatic stress disorder was more frequent among migrants with UDD. Limitations The study used cross-sectional prevalence data and could be biased by differences in the course of disease according to migrant status. Moreover, this design does not allow causality conclusion or generalization of the main findings. Conclusion Mood disorders are more common among migrants, especially UDD. Moreover, migrants with mood disorders presented with a more severe profile, with increased rates of psychotic and substance-use disorders.",

keywords = "Bipolar disorder, Comorbidities, Depressive disorder, Dysthymia, Migration",

author = "Baptiste Pignon and {Alexis Geoffroy}, Pierre and Pierre Thomas and Roelandt, {Jean Luc} and Benjamin Rolland and Craig Morgan and Guillaume Vaiva and Ali Amad",

year = "2017",

month = mar,

day = "1",

doi = "10.1016/j.jad.2016.12.039",

language = "English",

volume = "210",

pages = "174--180",

journal = "Journal of Affective Disorders",

issn = "0165-0327",

publisher = "Elsevier",

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TY - JOUR

T1 - Prevalence and clinical severity of mood disorders among first-, second- and third-generation migrants

AU - Pignon, Baptiste

AU - Alexis Geoffroy, Pierre

AU - Thomas, Pierre

AU - Roelandt, Jean Luc

AU - Rolland, Benjamin

AU - Morgan, Craig

AU - Vaiva, Guillaume

AU - Amad, Ali

PY - 2017/3/1

Y1 - 2017/3/1

N2 - Background The role of migration as a risk factor remains unknown for mood disorders because of poor data. We sought to examine the prevalence and severity of mood disorders (bipolar disorder (BD), unipolar depressive disorder (UDD) and dysthymia) in first, second, and third generation migrants in France. Methods The Mental Health in the General Population survey interviewed 38,694 individuals. The prevalence of lifetime mood disorders, comorbidities, and clinical features was compared between migrants and non-migrants and by generation. All analyses were adjusted for age, sex and level of education. Results The prevalence of any lifetime mood disorder was higher in migrants compared with non-migrants (OR=1.36, 95% CI [1.27–1.45]). This increased prevalence was significant for UDD (OR=1.44, 95% CI [1.34–1.54]), but not for BD (OR=1.15, 95% CI [0.96–1.36]) or dysthymia (OR=1.09, 95% CI [0.94–1.27]), although the prevalence of BD was increased in the third generation (OR=1.27, 95% CI [1.01–1.60]). Migrants with BD or UDD were more likely to display a comorbid psychotic disorder compared to non-migrants with BD or UDD. Cannabis-use disorders were more common in migrant groups for the 3 mood disorders, whereas alcohol-use disorders were higher in migrants with UDD. Posttraumatic stress disorder was more frequent among migrants with UDD. Limitations The study used cross-sectional prevalence data and could be biased by differences in the course of disease according to migrant status. Moreover, this design does not allow causality conclusion or generalization of the main findings. Conclusion Mood disorders are more common among migrants, especially UDD. Moreover, migrants with mood disorders presented with a more severe profile, with increased rates of psychotic and substance-use disorders.

AB - Background The role of migration as a risk factor remains unknown for mood disorders because of poor data. We sought to examine the prevalence and severity of mood disorders (bipolar disorder (BD), unipolar depressive disorder (UDD) and dysthymia) in first, second, and third generation migrants in France. Methods The Mental Health in the General Population survey interviewed 38,694 individuals. The prevalence of lifetime mood disorders, comorbidities, and clinical features was compared between migrants and non-migrants and by generation. All analyses were adjusted for age, sex and level of education. Results The prevalence of any lifetime mood disorder was higher in migrants compared with non-migrants (OR=1.36, 95% CI [1.27–1.45]). This increased prevalence was significant for UDD (OR=1.44, 95% CI [1.34–1.54]), but not for BD (OR=1.15, 95% CI [0.96–1.36]) or dysthymia (OR=1.09, 95% CI [0.94–1.27]), although the prevalence of BD was increased in the third generation (OR=1.27, 95% CI [1.01–1.60]). Migrants with BD or UDD were more likely to display a comorbid psychotic disorder compared to non-migrants with BD or UDD. Cannabis-use disorders were more common in migrant groups for the 3 mood disorders, whereas alcohol-use disorders were higher in migrants with UDD. Posttraumatic stress disorder was more frequent among migrants with UDD. Limitations The study used cross-sectional prevalence data and could be biased by differences in the course of disease according to migrant status. Moreover, this design does not allow causality conclusion or generalization of the main findings. Conclusion Mood disorders are more common among migrants, especially UDD. Moreover, migrants with mood disorders presented with a more severe profile, with increased rates of psychotic and substance-use disorders.

KW - Bipolar disorder

KW - Comorbidities

KW - Depressive disorder

KW - Dysthymia

KW - Migration

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U2 - 10.1016/j.jad.2016.12.039

DO - 10.1016/j.jad.2016.12.039

M3 - Article

SN - 0165-0327

VL - 210

SP - 174

EP - 180

JO - Journal of Affective Disorders

JF - Journal of Affective Disorders

ER -

Prevalence and clinical severity of mood disorders among first-, second- and third-generation migrants

Abstract

Keywords

UN SDGs

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