Prolonged survival in motor neuron disease: a descriptive study of the King's database 1990-2002

M R Turner, M J Parton, C E Shaw, P N Leigh, A Al-Chalabi

Research output: Contribution to journalArticlepeer-review

122 Citations (Scopus)

Abstract

Motor neuron disease is a clinically heterogeneous disease with significant differences in survival. The authors have characterised a subset of long term survivors seen in a tertiary clinic over a 12 year period in terms of clinical variables and demographics, comparing them with short term survivors and the remaining population. Thirty of 769 patients survived more than 10 years, corresponding to 4% of the total population. Significantly younger onset of disease symptoms and a predominance of pure upper motor neuron signs at presentation characterised the long term survivors, but factors traditionally regarded as being associated with poor prognosis were also well represented. For a few people with motor neuron disease there remains the hope, whatever the initial presentation, that their subsequent survival will be longer than expected.
Original languageEnglish
Pages (from-to)995 - 997
Number of pages3
JournalJournal of Neurology, Neurosurgery and Psychiatry
Volume74
Issue number7
DOIs
Publication statusPublished - 1 Jul 2003

Fingerprint

Dive into the research topics of 'Prolonged survival in motor neuron disease: a descriptive study of the King's database 1990-2002'. Together they form a unique fingerprint.

Cite this