Protease Inhibition

Garrit Peter Koller; Joerg Walter Bartsch

Protease Inhibition

Garrit Peter Koller (Inventor), Joerg Walter Bartsch (Inventor)

Research output: Patent

Abstract

The invention relates to a method for inhibiting an ADAM protease, comprising inhibiting binding to an integrin-binding loop of a disintegrin domain in the ADAM protease. Also provided are cyclic peptides which inhibit binding to an integrin-binding loop of an ADAM protease, as well as associated pharmaceutical compositions, uses and methods of treatment.

Original language	English
Patent number	USPTO 14/798,825
Publication status	Published - 11 Apr 2017

Keywords

CANCER-RESEARCH
chemotherapeutic approaches
PROTEASE
metastatic disease

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Cite this

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title = "Protease Inhibition",

abstract = "The invention relates to a method for inhibiting an ADAM protease, comprising inhibiting binding to an integrin-binding loop of a disintegrin domain in the ADAM protease. Also provided are cyclic peptides which inhibit binding to an integrin-binding loop of an ADAM protease, as well as associated pharmaceutical compositions, uses and methods of treatment.",

keywords = "CANCER-RESEARCH, chemotherapeutic approaches, PROTEASE, metastatic disease",

author = "Koller, {Garrit Peter} and Bartsch, {Joerg Walter}",

year = "2017",

month = apr,

day = "11",

language = "English",

type = "Patent",

note = "USPTO 14/798,825",

}

TY - PAT

T1 - Protease Inhibition

AU - Koller, Garrit Peter

AU - Bartsch, Joerg Walter

PY - 2017/4/11

Y1 - 2017/4/11

N2 - The invention relates to a method for inhibiting an ADAM protease, comprising inhibiting binding to an integrin-binding loop of a disintegrin domain in the ADAM protease. Also provided are cyclic peptides which inhibit binding to an integrin-binding loop of an ADAM protease, as well as associated pharmaceutical compositions, uses and methods of treatment.

AB - The invention relates to a method for inhibiting an ADAM protease, comprising inhibiting binding to an integrin-binding loop of a disintegrin domain in the ADAM protease. Also provided are cyclic peptides which inhibit binding to an integrin-binding loop of an ADAM protease, as well as associated pharmaceutical compositions, uses and methods of treatment.

KW - CANCER-RESEARCH

KW - chemotherapeutic approaches

KW - PROTEASE

KW - metastatic disease

M3 - Patent

M1 - USPTO 14/798,825

ER -

Protease Inhibition

Abstract

Keywords

UN SDGs

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