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Protease Inhibition

Research output: Patent

Original languageEnglish
Patent numberUSPTO 14/798,825
Publication statusPublished - 11 Apr 2017

King's Authors


The invention relates to a method for inhibiting an ADAM protease, comprising inhibiting binding to an integrin-binding loop of a disintegrin domain in the ADAM protease. Also provided are cyclic peptides which inhibit binding to an integrin-binding loop of an ADAM protease, as well as associated pharmaceutical compositions, uses and methods of treatment.

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