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Proteomic analysis of secretory proteins and vesicles in vascular research

Research output: Contribution to journalLiterature review

G Pula, S Perera, M Prokopi, A Sidibe, C M Boulanger, M Mayr

Original languageEnglish
Pages (from-to)882 - 891
Number of pages10
JournalProteomics Clinical Applications
Volume2
Issue number6
DOIs
Publication statusPublished - Jun 2008

King's Authors

Abstract

The release of proteins and membrane vesicles in the bloodstream regulates diverse vascular processes, both physiological, such as angiogenesis and haemostasis, and pathological, such as atherosclerosis and atherothrombosis. Proteomics, beside its canonical application for the expression profiling in cells and organs, can be applied to the study of secreted proteins and microvesicles, which play a significant role in the homeostasis of the vasculature, and the development of the atherosclerotic disease

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