Proteomics for Brain Disorders-The Promise for Biomarkers

Malcolm Ward, Andreas Guentert, James Campbell, Ian Pike

    Research output: Chapter in Book/Report/Conference proceedingConference paper

    5 Citations (Scopus)

    Abstract

    Biomarkers of brain disorders are urgently needed to aid diagnosis, monitor disease progression, and, as new medicines are introduced, detect the patient's response to treatment. Proteomics provides the opportunity to discover novel biochemical markers based on protein or peptide changes, either in concentration levels or post-translational modification status. There are many challenges associated with proteomics studies, and this article represents a review of the issues discussed during the proteomics breakout sessions held at the Biomarkers for Brain Disorders conference in Oxford in January 2009. Although to date, there are very few qualified biomarkers that have arisen as a result of proteomics efforts, we remain optimistic that proteomics will deliver biomarkers for brain disorders. To be successful, we need to recognize that such endeavors are likely to require multidisciplinary teams and continued collaboration between academia, the biotechnology industry, and the pharmaceutical sector.
    Original languageEnglish
    Title of host publicationUnknown
    Place of PublicationOXFORD
    PublisherBlackwell Publishing
    Pages68 - 74
    Number of pages7
    Volume1180
    ISBN (Print)978-1-57331-772-6
    DOIs
    Publication statusPublished - 2009
    EventConference on Biomarkers in Brain Disease - Oxford, ENGLAND
    Duration: 26 Jan 200928 Jan 2009

    Publication series

    NameBIOMARKERS IN BRAIN DISEASE

    Conference

    ConferenceConference on Biomarkers in Brain Disease
    CityOxford, ENGLAND
    Period26/01/200928/01/2009

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