Pruritus may precede abnormal liver function tests in pregnant women with obstetric cholestasis: a longitudinal analysis

TY - JOUR

T1 - Pruritus may precede abnormal liver function tests in pregnant women with obstetric cholestasis: a longitudinal analysis

AU - Kenyon, A P

AU - Piercy, C N

AU - Girling, J

AU - Williamson, C

AU - Tribe, R M

AU - Shennan, A H

PY - 2001

Y1 - 2001

N2 - Obstetric cholestasis is a liver disorder unique to pregnancy, which typically presents with pruritus. However, pruritus is common in pregnancy and the diagnosis of obstetric cholestasis is confirmed by finding abnormal liver function. We report 10 cases in which pruritus occurred before any, abnormality in liver function tests (including total serum bile acids) and discuss the implications or this for clinical practice.

AB - Obstetric cholestasis is a liver disorder unique to pregnancy, which typically presents with pruritus. However, pruritus is common in pregnancy and the diagnosis of obstetric cholestasis is confirmed by finding abnormal liver function. We report 10 cases in which pruritus occurred before any, abnormality in liver function tests (including total serum bile acids) and discuss the implications or this for clinical practice.

UR - http://www.scopus.com/inward/record.url?scp=0035169998&partnerID=8YFLogxK

U2 - 10.1016/S0306-5456(01)00281-9

DO - 10.1016/S0306-5456(01)00281-9

M3 - Article

VL - 108

SP - 1190

EP - 1192

JO - British Journal of Obstetrics and Gynaecology

JF - British Journal of Obstetrics and Gynaecology

IS - 11

ER -