Pruritus may precede abnormal liver function tests in pregnant women with obstetric cholestasis: a longitudinal analysis

A P Kenyon; C N Piercy; J Girling; C Williamson; R M Tribe; A H Shennan

Pruritus may precede abnormal liver function tests in pregnant women with obstetric cholestasis: a longitudinal analysis

A P Kenyon, C N Piercy, J Girling, C Williamson, R M Tribe, A H Shennan

Women & Children's Health

Research output: Contribution to journal › Article › peer-review

61 Citations (Scopus)

Abstract

Obstetric cholestasis is a liver disorder unique to pregnancy, which typically presents with pruritus. However, pruritus is common in pregnancy and the diagnosis of obstetric cholestasis is confirmed by finding abnormal liver function. We report 10 cases in which pruritus occurred before any abnormality in liver function tests (including total serum bile acids) and discuss the implications of this for clinical practice.

Original language	English
Pages (from-to)	1190-2
Number of pages	3
Journal	BJOG
Volume	108
Issue number	11
Publication status	Published - Nov 2001

Keywords

Adult
Cholestasis
Female
Humans
Liver Function Tests
Longitudinal Studies
Pregnancy
Pregnancy Complications
Prospective Studies
Pruritus

Cite this

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title = "Pruritus may precede abnormal liver function tests in pregnant women with obstetric cholestasis: a longitudinal analysis",

abstract = "Obstetric cholestasis is a liver disorder unique to pregnancy, which typically presents with pruritus. However, pruritus is common in pregnancy and the diagnosis of obstetric cholestasis is confirmed by finding abnormal liver function. We report 10 cases in which pruritus occurred before any abnormality in liver function tests (including total serum bile acids) and discuss the implications of this for clinical practice.",

keywords = "Adult, Cholestasis, Female, Humans, Liver Function Tests, Longitudinal Studies, Pregnancy, Pregnancy Complications, Prospective Studies, Pruritus",

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year = "2001",

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TY - JOUR

T1 - Pruritus may precede abnormal liver function tests in pregnant women with obstetric cholestasis

T2 - a longitudinal analysis

AU - Kenyon, A P

AU - Piercy, C N

AU - Girling, J

AU - Williamson, C

AU - Tribe, R M

AU - Shennan, A H

PY - 2001/11

Y1 - 2001/11

N2 - Obstetric cholestasis is a liver disorder unique to pregnancy, which typically presents with pruritus. However, pruritus is common in pregnancy and the diagnosis of obstetric cholestasis is confirmed by finding abnormal liver function. We report 10 cases in which pruritus occurred before any abnormality in liver function tests (including total serum bile acids) and discuss the implications of this for clinical practice.

AB - Obstetric cholestasis is a liver disorder unique to pregnancy, which typically presents with pruritus. However, pruritus is common in pregnancy and the diagnosis of obstetric cholestasis is confirmed by finding abnormal liver function. We report 10 cases in which pruritus occurred before any abnormality in liver function tests (including total serum bile acids) and discuss the implications of this for clinical practice.

KW - Adult

KW - Cholestasis

KW - Female

KW - Humans

KW - Liver Function Tests

KW - Longitudinal Studies

KW - Pregnancy

KW - Pregnancy Complications

KW - Prospective Studies

KW - Pruritus

M3 - Article

C2 - 11762661

SN - 1470-0328

VL - 108

SP - 1190

EP - 1192

JO - BJOG

JF - BJOG

IS - 11

ER -

Pruritus may precede abnormal liver function tests in pregnant women with obstetric cholestasis: a longitudinal analysis

Abstract

Keywords

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