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Psoriasis and Genetics

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Psoriasis and Genetics. / Dand, Nick; Mahil, Satveer K; Capon, Francesca; Smith, Catherine H; Simpson, Michael A; Barker, Jonathan N.

In: Acta Dermato-Venereologica, Vol. 100, No. 100-year theme: Psoriasis, adv00030, 30.01.2020, p. 54-64.

Research output: Contribution to journalReview article

Harvard

Dand, N, Mahil, SK, Capon, F, Smith, CH, Simpson, MA & Barker, JN 2020, 'Psoriasis and Genetics', Acta Dermato-Venereologica, vol. 100, no. 100-year theme: Psoriasis, adv00030, pp. 54-64. https://doi.org/10.2340/00015555-3384

APA

Dand, N., Mahil, S. K., Capon, F., Smith, C. H., Simpson, M. A., & Barker, J. N. (2020). Psoriasis and Genetics. Acta Dermato-Venereologica, 100(100-year theme: Psoriasis), 54-64. [adv00030]. https://doi.org/10.2340/00015555-3384

Vancouver

Dand N, Mahil SK, Capon F, Smith CH, Simpson MA, Barker JN. Psoriasis and Genetics. Acta Dermato-Venereologica. 2020 Jan 30;100(100-year theme: Psoriasis):54-64. adv00030. https://doi.org/10.2340/00015555-3384

Author

Dand, Nick ; Mahil, Satveer K ; Capon, Francesca ; Smith, Catherine H ; Simpson, Michael A ; Barker, Jonathan N. / Psoriasis and Genetics. In: Acta Dermato-Venereologica. 2020 ; Vol. 100, No. 100-year theme: Psoriasis. pp. 54-64.

Bibtex Download

@article{71bd468166904cb894e150d3aa7b633c,
title = "Psoriasis and Genetics",
abstract = "Psoriasis is a common inflammatory skin disease caused by the interplay between multiple genetic and environmental risk factors. This review summarises recent progress in elucidating the genetic basis of psoriasis, particularly through large genome-wide association studies. We illustrate the power of genetic analyses for disease stratification. Psoriasis can be stratified by phenotype (common plaque versus rare pustular variants), or by outcome (prognosis, comorbidities, response to treatment); recent progress has been made in delineating the genetic contribution in each of these areas. We also highlight how genetic data can directly inform the development of effective psoriasis treatments.",
keywords = "disease progression, genetics, precision medicine, psoriasis, treatment outcome",
author = "Nick Dand and Mahil, {Satveer K} and Francesca Capon and Smith, {Catherine H} and Simpson, {Michael A} and Barker, {Jonathan N}",
year = "2020",
month = jan,
day = "30",
doi = "10.2340/00015555-3384",
language = "English",
volume = "100",
pages = "54--64",
journal = "Acta Dermato-Venereologica",
issn = "0001-5555",
publisher = "Society for the Publication of Acta Dermato-Venereologica",
number = "100-year theme: Psoriasis",

}

RIS (suitable for import to EndNote) Download

TY - JOUR

T1 - Psoriasis and Genetics

AU - Dand, Nick

AU - Mahil, Satveer K

AU - Capon, Francesca

AU - Smith, Catherine H

AU - Simpson, Michael A

AU - Barker, Jonathan N

PY - 2020/1/30

Y1 - 2020/1/30

N2 - Psoriasis is a common inflammatory skin disease caused by the interplay between multiple genetic and environmental risk factors. This review summarises recent progress in elucidating the genetic basis of psoriasis, particularly through large genome-wide association studies. We illustrate the power of genetic analyses for disease stratification. Psoriasis can be stratified by phenotype (common plaque versus rare pustular variants), or by outcome (prognosis, comorbidities, response to treatment); recent progress has been made in delineating the genetic contribution in each of these areas. We also highlight how genetic data can directly inform the development of effective psoriasis treatments.

AB - Psoriasis is a common inflammatory skin disease caused by the interplay between multiple genetic and environmental risk factors. This review summarises recent progress in elucidating the genetic basis of psoriasis, particularly through large genome-wide association studies. We illustrate the power of genetic analyses for disease stratification. Psoriasis can be stratified by phenotype (common plaque versus rare pustular variants), or by outcome (prognosis, comorbidities, response to treatment); recent progress has been made in delineating the genetic contribution in each of these areas. We also highlight how genetic data can directly inform the development of effective psoriasis treatments.

KW - disease progression

KW - genetics

KW - precision medicine

KW - psoriasis

KW - treatment outcome

UR - http://www.scopus.com/inward/record.url?scp=85079019267&partnerID=8YFLogxK

U2 - 10.2340/00015555-3384

DO - 10.2340/00015555-3384

M3 - Review article

C2 - 31971603

VL - 100

SP - 54

EP - 64

JO - Acta Dermato-Venereologica

JF - Acta Dermato-Venereologica

SN - 0001-5555

IS - 100-year theme: Psoriasis

M1 - adv00030

ER -

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