Psychiatric co-morbidity among subjects with heroin and cocaine use disorders and its association with HCV infection

TY - JOUR

T1 - Psychiatric co-morbidity among subjects with heroin and cocaine use disorders and its association with HCV infection

AU - Wang, Mei

AU - Finch, Emily

AU - Wolff, Kim

PY - 2013/7/17

Y1 - 2013/7/17

N2 - Aim: This study aims to determine whether psychiatric co-morbidity is associated with HCV infection in a substance misuse population.Methods: We identified all subjects in the National Drug Treatment Monitoring System (NDTMS) during the period January 2007-December 2010 for whom information was recorded which identified their psychiatric co-morbidity status and their HCV status. Multivariate analysis was used to identify risk factors that could predict HCV infection.Results and conclusions: The HCV prevalence rate was 32%. HCV infected subjects were younger (21.4% versus 23.1%) when they first started to use drugs, they were more likely to be white (85.1% versus 13.1%) and male (74% versus 72.6%), to have urgent housing problems (13.0% versus 9.7%), to inject (42.8% versus 18.8%), and to share injecting paraphernalia (35.4% versus 9.2%). After adjusting for demographics and drug and alcohol use behaviours, the Odds Ratio of psychiatric co-morbidity for HCV infection was 1.33 (95% CI 1.01-1.75). The results suggest that psychiatric co-morbidity is associated of HCV infection.Clinical implications: It is important to take psychiatric co-morbidity into account when treating these patients and designing intervention strategies.

AB - Aim: This study aims to determine whether psychiatric co-morbidity is associated with HCV infection in a substance misuse population.Methods: We identified all subjects in the National Drug Treatment Monitoring System (NDTMS) during the period January 2007-December 2010 for whom information was recorded which identified their psychiatric co-morbidity status and their HCV status. Multivariate analysis was used to identify risk factors that could predict HCV infection.Results and conclusions: The HCV prevalence rate was 32%. HCV infected subjects were younger (21.4% versus 23.1%) when they first started to use drugs, they were more likely to be white (85.1% versus 13.1%) and male (74% versus 72.6%), to have urgent housing problems (13.0% versus 9.7%), to inject (42.8% versus 18.8%), and to share injecting paraphernalia (35.4% versus 9.2%). After adjusting for demographics and drug and alcohol use behaviours, the Odds Ratio of psychiatric co-morbidity for HCV infection was 1.33 (95% CI 1.01-1.75). The results suggest that psychiatric co-morbidity is associated of HCV infection.Clinical implications: It is important to take psychiatric co-morbidity into account when treating these patients and designing intervention strategies.

KW - Psychiatric co-morbidity

KW - HCV infection

KW - heroin and cocaine use

KW - CHRONIC HEPATITIS-C

KW - NATIONAL EPIDEMIOLOGIC SURVEY

KW - SEVERE MENTAL-ILLNESS

KW - SUBSTANCE-ABUSE

KW - VIRUS-INFECTION

KW - RISK BEHAVIORS

KW - UNITED-STATES

KW - DRUG-USERS

KW - COMORBIDITY

KW - PREVALENCE

U2 - 10.3109/14659891.2013.784370

DO - 10.3109/14659891.2013.784370

M3 - Article

SN - 1465-9891

VL - 19

SP - 245

EP - 250

JO - Journal of Substance Use

JF - Journal of Substance Use

IS - 3

ER -