@article{7e25283b10d74ccfaa7ecfd2dff8cf69,
title = "Psychiatric comorbidity is common in dystonia and other movement disorders",
abstract = "Objective: To determine rates of psychiatric comorbidity in a clinical sample of childhood movement disorders (MDs). Design: Cohort study. Setting: Tertiary children's hospital MD clinics in Sydney, Australia and London, UK. Patients: Cases were children with tic MDs (n=158) and non-tic MDs (n=102), including 66 children with dystonia. Comparison was made with emergency department controls (n=100), neurology controls with peripheral neuropathy or epilepsy (n=37), and community controls (n=10 438). Interventions: On-line development and well-being assessment which was additionally clinically rated by experienced child psychiatrists. Main outcome measures: Diagnostic schedule and manual of mental disorders-5 criteria for psychiatric diagnoses. Results: Psychiatric comorbidity in the non-tic MD cohort (39.2%) was comparable to the tic cohort (41.8%) (not significant). Psychiatric comorbidity in the non-tic MD cohort was greater than the emergency control group (18%, p<0.0001) and the community cohort (9.5%, p<0.00001), but not the neurology controls (29.7%, p=0.31). Almost half of the patients within the tic cohort with psychiatric comorbidity were receiving medical psychiatric treatment (45.5%) or psychology interventions (43.9%), compared with only 22.5% and 15.0%, respectively, of the non-tic MD cohort with psychiatric comorbidity. Conclusions: Psychiatric comorbidity is common in non-tic MDs such as dystonia. These psychiatric comorbidities appear to be under-recognised and undertreated. ",
keywords = "neurology, psychology",
author = "Lorentzos, {Michelle S.} and Isobel Heyman and Baig, {Benjamin J.} and Coughtrey, {Anna E.} and Andrew McWilliams and Dossetor, {David R.} and Waugh, {Mary Clare} and Evans, {Ruth A.} and Josie Hollywood and Joshua Burns and Menezes, {Manoj P.} and Mohammad, {Shekeeb S.} and Padraig Grattan-Smith and Gorman, {Kathleen M.} and Crowe, {Belinda H.A.} and Robert Goodman and Kurian, {Manju A.} and Dale, {Russell C.}",
note = "Funding Information: JB is funded by the Australian Department of Health (Medical Research Future Fund), US National Institutes of Health, Charcot-Marie Tooth Association of Australia, Charcot-Marie Tooth Association (USA), Diabetes Australia, Elizabeth Lottie May Rosenthal Bone Bequest, Perpetual Limited, Humpty Dumpty Foundation. Consultancies: Pharnext SA, Charcot Marie Tooth Association (USA) Advisory Board (Clinical Experts), Research & Innovation Funding Information: Funding JB is funded by the Australian Department of Health (Medical Research Future Fund), US National Institutes of Health, Charcot-Marie Tooth Association of Australia, Charcot-Marie Tooth Association (USA), Diabetes Australia, Elizabeth Lottie May Rosenthal Bone Bequest, Perpetual Limited, Humpty Dumpty Foundation. Consultancies: Pharnext SA, Charcot Marie Tooth Association (USA) Advisory Board (Clinical Experts), Research & Innovation Advisory Board, Siriraj Hospital, Mahidol University, Bangkok, Thailand Competing interests RG and his family are the owners of Youthinmind Limited, which provides no-cost and low-cost measures of child mental health, including the Strengths and Difficulties Questionnaire (SDQ) and development and well-being assessment (DAWBA). Publisher Copyright: {\textcopyright} 2021 Author(s). Copyright: Copyright 2021 Elsevier B.V., All rights reserved.",
year = "2021",
month = jan,
day = "1",
doi = "10.1136/archdischild-2020-319541",
language = "English",
volume = "106",
pages = "62--67",
journal = "Archives of Disease in Childhood",
issn = "0003-9888",
publisher = "BMJ Publishing Group Ltd",
number = "1",
}